Moussa B. H. Youdim

1940 -

photo credits: Wikimedia Commons

país de nacionalidade: Irão, Israel

línguas faladas, escritas ou assinadas: inglês, hebraico

alma mater: Universidade McGill, Universidade de Londres

ocupação: neurocientista, professor universitário, investigador

distinção: The EMET Prize for Art, Science and Culture, Prêmio Israel

Moussa B. H. Youdim is an internationally renowned Israeli neuroscientist specializing in neurochemistry and neuropharmacology. He is the discoverer of both monoamine oxidase (MAO) B inhibitors l-deprenyl (Selegiline) and rasagiline (Azilect) as anti-Parkinson drugs which possess neuroprotective activities. He is currently professor emeritus at Technion - Faculty of Medicine and President of Youdim Pharmaceuticals. Source: Wikipedia (en)

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Articles 217

Date

Title

Authors

2020-05-08

Creation of a gene expression classifier for predicting Parkinson's disease rate of progression

Moussa B. H. Youdim, Peter Riederer, Danit Mechlovich
2018-10-19

Monoamine oxidase inhibitors, and iron chelators in depressive illness and neurodegenerative diseases

Moussa B. H. Youdim
2018-07-17

A promising drug candidate for the treatment of glaucoma based on a P2Y6-receptor agonist

Bilha Fischer, Moussa B. H. Youdim, Orly Weinreb
2017-06-09

Monoamine oxidase A upregulated by chronic intermittent hypoxia activates indoleamine 2,3-dioxygenase and neurodegeneration

Moussa B. H. Youdim, George Lim Tipoe
2017-05-29

The novel multitarget iron chelating and propargylamine drug M30 affects APP regulation and processing activities in Alzheimer's disease models

Orly Weinreb, Moussa B. H. Youdim, Danit Mechlovich, Lana Kupershmidt
2017-04-11

The involvement of BDNF-CREB signaling pathways in the pharmacological mechanism of combined SSRI- antipsychotic treatment in schizophrenia

Moussa B. H. Youdim, Nina Mandiuk, Orly Weinreb
2017-10-01

Iron-Chelating Drugs Enhance Cone Photoreceptor Survival in a Mouse Model of Retinitis Pigmentosa

Bo Peng, Bin Lin, Moussa B. H. Youdim, Orly Weinreb
2016-05-13

Beneficial Effects of Multitarget Iron Chelator on Central Nervous System and Gastrocnemius Muscle in SOD1(G93A) Transgenic ALS Mice.

Moussa B. H. Youdim, Sagit Golko-Perez, Orly Weinreb
2016-09-01

Inhibition of caspase-9 aggravates acute liver injury through suppression of cytoprotective autophagy

Bin Lin, Kwok-Fai So, Moussa B. H. Youdim
2016

Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease

Irene Bolea, Mercedes Unzeta
2016-11-21

M30 Antagonizes Indoleamine 2,3-Dioxygenase Activation and Neurodegeneration Induced by Corticosterone in the Hippocampus

Moussa B. H. Youdim, George Lim Tipoe
2016-10-28

Anti-inflammatory and protective effects of MT-031, a novel multitarget MAO-A and AChE/BuChE inhibitor in scopolamine mouse model and inflammatory cells

Orly Weinreb, Moussa B. H. Youdim
2016-07-21

Neurorescue by a ROS Decomposition Catalyst

Moussa B. H. Youdim, S Mandel, Irena Saltsman, Atif Mahammed
2016-06-15

Design, synthesis and evaluation of novel dual monoamine-cholinesterase inhibitors as potential treatment for Alzheimer's disease

Orly Weinreb, Moussa B. H. Youdim
2016-11-08

A Novel Iron Chelator-Radical Scavenger Ameliorates Motor Dysfunction and Improves Life Span and Mitochondrial Biogenesis in SOD1G93A ALS Mice.

Moussa B. H. Youdim, Sagit Golko-Perez, Orly Weinreb
2015-08-01

TVP1022: A Novel Cardioprotective Drug Attenuates Left Ventricular Remodeling After Ischemia/Reperfusion in Pigs

Ofer Binah, Yaron D Barac, Moussa B. H. Youdim, Itzchak Angel, Rona Shofti, Assaf Malka, Noa Bachner-Hinenzon
2015-08-29

Neuroprotective effects of multifaceted hybrid agents targeting MAO, cholinesterase, iron and β-amyloid in ageing and Alzheimer's disease

Orly Weinreb, Moussa B. H. Youdim
2015-04-01

Theodore Lionel Sourkes obituary.

A Claudio Cuello, Moussa B. H. Youdim
2015-02-09

New approaches to treating Alzheimer's disease

Moussa B. H. Youdim
2015-02-04

A novel antioxidant multitarget iron chelator M30 protects hepatocytes against ethanol-induced injury

Jia Xiao, Bin Lin, Moussa B. H. Youdim
2015-11-18

Additive Neuroprotective Effects of the Multifunctional Iron Chelator M30 with Enriched Diet in a Mouse Model of Amyotrophic Lateral Sclerosis

Orly Weinreb, Moussa B. H. Youdim, S Mandel, Lana Kupershmidt, Sagit Golko-Perez
2015-07-06

Multi-target iron-chelators improve memory loss in a rat model of sporadic Alzheimer's disease

Ana Knezovic, Moussa B. H. Youdim, S Mandel, Peter Riederer, Melita Salkovic-Petrisic
2015-05-21

Effect of long-term treatment with rasagiline on cognitive deficits and related molecular cascades in aged mice

Moussa B. H. Youdim, Felix Badinter, Orly Weinreb
2015-06-15

Beneficial behavioral, neurochemical and molecular effects of 1-(R)-aminoindan in aged mice.

Moussa B. H. Youdim, Felix Badinter, Orly Weinreb
2015-05-01

Improvement in verbal memory following SSRI augmentation of antipsychotic treatment is associated with changes in the expression of mRNA encoding for the GABA-A receptor and BDNF in PMC of schizophrenic patients.

Moussa B. H. Youdim, Nina Mandiuk, Ehud Susser, Lena Danovich, Orly Weinreb
2015-11-13

N-Methyl, N-propynyl-2-phenylethylamine (MPPE), a Selegiline Analog, Attenuates MPTP-induced Dopaminergic Toxicity with Guaranteed Behavioral Safety: Involvement of Inhibitions of Mitochondrial Oxidative Burdens and p53 Gene-elicited Pro-apoptotic C

Moussa B. H. Youdim
2014-02-01

The novel multi-target iron chelator, M30 modulates HIF-1α-related glycolytic genes and insulin signaling pathway in the frontal cortex of APP/PS1 Alzheimer's disease mice.

Moussa B. H. Youdim, S Mandel, Danit Mechlovich, Orly Weinreb
2014-04-29

Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease.

Alejandro Romero Martínez, Gerard Esteban, Ignacio Moraleda, Ana Patricia Fernández Fernández, Isabel Iriepa, Mercedes Unzeta, Moussa B. H. Youdim
2014-01-01

Promises of novel multi-target neuroprotective and neurorestorative drugs for Parkinson's disease

Orly Weinreb, Moussa B. H. Youdim, Lana Kupershmidt
2014-01-23

From single target to multitarget/network therapeutics in Alzheimer's therapy

Moussa B. H. Youdim
2014-12-01

Molecular targets of the multifunctional iron-chelating drug, M30, in the brains of mouse models of type 2 diabetes mellitus

Orly Weinreb, Moussa B. H. Youdim, Danit Mechlovich
2014-01-06

DJ-1 deficiency triggers microglia sensitivity to dopamine toward a pro-inflammatory phenotype that is attenuated by rasagiline

Orly Weinreb, Moussa B. H. Youdim, S Mandel

Human - wd:Q16105430

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