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Human proto-oncogene N-myc encodes nuclear proteins that bind DNA

Author

J. Michael Bishop

1936 -

Graeme William Ramsay

1932 - 2017

Published in: Molecular and Cellular Biology

Date of publication: December 1986

Language: English

Main subject: MYCN proto-oncogene, bHLH transcription factor, regulation of transcription by RNA polymerase II

Bibliographic databases:

Cites articles 45

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Intracellular protein degradation in mammalian and bacterial cells: Part 2
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Transcripts from the cellular homologs of retroviral oncogenes: distribution among chicken tissues,Transcripts from the Cellular Homologs of Retroviral Oncogenes: Distribution Among Chicken Tissues
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Cloning and characterization of different human sequences related to the onc gene (v-myc) of avian myelocytomatosis virus (MC29)

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Discrete regions of simian virus 40 large T antigen are required for nonspecific and viral origin-specific DNA binding
March 1, 1982

Nuclear localization and DNA binding of the transforming gene product of avian myelocytomatosis virus
January 1, 1982

Phosphorylation of specific sites in the gag-myc polyproteins encoded by MC29-type viruses correlates with their transforming ability
June 1, 1982

Nuclear location of the putative transforming protein of avian myelocytomatosis virus
August 18, 1983

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
November 1, 1983

Translocations among antibody genes in human cancer
November 1, 1983

Identification of nuclear proteins encoded by viral and cellular myc oncogenes
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Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

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Proteins encoded by v-myc and c-myc oncogenes: Identification and localization in acute leukemia virus transformants and bursal lymphoma cell lines
December 1, 1983

Transposition and amplification of oncogene-related sequences in human neuroblastomas
December 1, 1983

Regulation of myc gene expression in HL-60 leukaemia cells by a vitamin D metabolite
December 1, 1983

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor
June 8, 1984

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

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Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation
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Extreme instability of myc mRNA in normal and transformed human cells
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Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma
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The protein encoded by the human proto-oncogene c-myc

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Expression and amplification of the N-myc gene in primary retinoblastoma
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Regulation of heat shock protein 70 gene expression by c-myc
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Nuclear localization and DNA binding properties of a protein expressed by human c-myc oncogene
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Subcellular localization of proteins encoded by oncogenes of avian myeloblastosis virus and avian leukemia virus E26 and by the chicken c-myb gene
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Viral and cellular fos proteins: a comparative analysis

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Antibodies to human c-myc oncogene product: evidence of an evolutionarily conserved protein induced during cell proliferation
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Spatial and temporal pattern of cellular myc oncogene expression in developing human placenta: implications for embryonic cell proliferation
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Activated expression of the N-myc gene in human neuroblastomas and related tumors
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Expression and characterization of the human c-myc DNA-binding protein
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V-myc- and c-myc-encoded proteins are associated with the nuclear matrix

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