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Flexibility in DNA recombination: structure of the lambda integrase catalytic core

Published in: Science

Date of publication: April 4, 1997

Language: English

Bibliographic databases:

Cites articles 48

Date

Title

Authors

October 1, 1978

The bacteriophage lambda int gene product. A filter assay for genetic recombination, purification of int, and specific binding to DNA
May 1, 1983

Patterns of lambda Int recognition in the regions of strand exchange
October 1, 1983

Role for DNA homology in site-specific recombination. The isolation and characterization of a site affinity mutant of coliphage lambda
January 1, 1984

Site-specific recombination systems of phages phi 80 and P22: binding sites of integration host factor and recombination-induced mutations
January 1, 1988

The mechanism of conservative site-specific recombination
August 1, 1988

Step-arrest mutants of FLP recombinase: implications for the catalytic mechanism of DNA recombination
September 1, 1988

Autonomous DNA binding domains of lambda integrase recognize two different sequence families
June 1, 1988

Suicide recombination substrates yield covalent lambda integrase-DNA complexes and lead to identification of the active site tyrosine
February 20, 1989

FLP recombinase of the 2 microns circle plasmid of Saccharomyces cerevisiae bends its DNA target. Isolation of FLP mutants defective in DNA bending
1989

Dynamic, structural, and regulatory aspects of lambda site-specific recombination
December 1, 1989

Excision and insertion of the conjugative transposon Tn916 involves a novel recombination mechanism
October 1, 1990

Identification of the active site tyrosine of Flp recombinase. Possible relevance of its location to the mechanism of recombination
January 1, 1990

Protein multiple sequence alignment and flexible pattern matching
December 1, 1990

The crystal structure of the catalytic domain of the site-specific recombination enzyme gamma delta resolvase at 2.7 A resolution

,
January 30, 1992

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures
December 1992

Catalysis by site-specific recombinases
August 1, 1992

X-ray structure of the DNase I-d(GGTATACC)2 complex at 2.3 A resolution
January 1, 1992

Evidence for a second conserved arginine residue in the integrase family of recombination proteins
May 1, 1992

DNA cleavage in trans by the active site tyrosine during Flp recombination: switching protein partners before exchanging strands
January 1993

ALSCRIPT: a tool to format multiple sequence alignments
September 5, 1993

Protein structure comparison by alignment of distance matrices
June 1, 1993

SETOR: hardware-lighted three-dimensional solid model representations of macromolecules
June 1, 1993

Crystal structure of cyclin-dependent kinase 2

,
June 1, 1993

Site-specific genetic recombination: hops, flips, and flops
October 1, 1993

Mechanistic and structural complexity in the site-specific recombination pathways of Int and FLP.
December 1, 1993

Complementation of bacteriophage lambda integrase mutants: evidence for an intersubunit active site
April 1, 1993

Sequence requirements for target activity in site-specific recombination mediated by the Int protein of transposon Tn 1545.
January 1, 1993

Improvement of macromolecular electron-density maps by the simultaneous application of real and reciprocal space constraints
May 1, 1993

2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor
January 13, 1994

Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I
May 1, 1994

Refinement of gamma delta resolvase reveals a strikingly flexible molecule
December 23, 1994

Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

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