Lara M. Mangravite

Occupation: researcher

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Articles 77

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Title

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1997-06

Differential Iron(II) Affinity of the Sites of the Diiron Cluster in Protein R2 of Escherichia coli Ribonucleotide Reductase: Tracking the Individual Sites through the O2 Activation Sequence

Lara M. Mangravite
1998-01-01

Electron injection through a specific pathway determines the outcome of oxygen activation at the diiron cluster in the F208Y mutant of Escherichia coli ribonucleotide reductase protein R2

Lara M. Mangravite
2001-08-01

Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate

Carolyn L. Cummins, Lara M. Mangravite
2003-05

Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells

Lara M. Mangravite
2003-05-13

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

Lara M. Mangravite, Thomas E Ferrin
2003-10-31

Nucleoside transporters in the disposition and targeting of nucleoside analogs in the kidney

Lara M. Mangravite
2003-02-01

Sorting of rat SPNT in renal epithelium is independent of N-glycosylation

Lara M. Mangravite
2004-03-01

Functional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations

Lara M. Mangravite, Thomas E Ferrin
2004-06-01

PharmGKB update: III. Genetic variants of SLC22A1, solute carrier family 22 (organic cation transporter), member 1.

Lara M. Mangravite, Thomas E Ferrin
2005-11-15

The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics

Lara M. Mangravite, Thomas E Ferrin
2007-08-01

Pharmacogenomics of statin response.

Lara M. Mangravite
2007-09-01

Fatty acid desaturase regulation in adipose tissue by dietary composition is independent of weight loss and is correlated with the plasma triacylglycerol response

Lara M. Mangravite
2008-09-15

Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins

Lara M. Mangravite, Maxwell A Ruby, John E. Casida
2008-03-10

Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment

Lara M. Mangravite, Jerome I Rotter, Kent D Taylor, Deborah A Nickerson
2008-12-01

Pharmacogenomics of statin response

Lara M. Mangravite
2009-12

Pharmacogenomic discovery using cell-based models

Lara M. Mangravite, Kelan G Tantisira
2009-03

Research Highlights

Lara M. Mangravite, Alfons Navarro
2010

Genome-wide association of lipid-lowering response to statins in combined study populations

Matthew Stephens, Lara M. Mangravite, Catherine A. McCarty, Jerome I Rotter, Paul Ridker, Daniel I Chasman, Deborah A Nickerson, Mathew J Barber, Russell A Wilke
2010-04-22

Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin

Lara M. Mangravite, Jerome I Rotter, Deborah A Nickerson
2010-03-01

PharmGKB very important pharmacogene: SLCO1B1.

Russ Altman, Lara M. Mangravite
2011-10-26

Changes in atherogenic dyslipidemia induced by carbohydrate restriction in men are dependent on dietary protein source

Lara M. Mangravite
2011-04-04

Developing Predictive Molecular Maps of Human Disease through Community-based Modeling

Lara M. Mangravite, Christine Suver, Stephen Friend, Michael Kellen
2011-04-04

Developing Predictive Molecular Maps of Human Disease through Community-based Modeling

Christine Suver, Stephen Friend, Michael Kellen, Lara M. Mangravite
2012

RHOA is a modulator of the cholesterol-lowering effects of statin

Lara M. Mangravite, Elizabeth Theusch
2012-01-27

Developing predictive molecular maps of human disease through community-based modeling

Christine Suver, Brian M Bot, Lara M. Mangravite, Stephen Friend, Michael Kellen
2012-09-05

Effects of dietary saturated fat on LDL subclasses and apolipoprotein CIII in men

Lara M. Mangravite
2012-10-16

Transcriptome correlation analysis identifies two unique craniosynostosis subtypes associated with IRS1 activation

Lara M. Mangravite
2012-11-01

A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.

Lara M. Mangravite, Alison Motsinger-Reif, Tammy M Havener
2013-10-17

A statin-dependent QTL for GATM expression is associated with statin-induced myopathy

Lara M. Mangravite, Jerome I Rotter, Sarah Parish, Paul Ridker, Daniel I Chasman, Deborah A Nickerson, Yen-Chu Chen, Russell A Wilke, Jemma C Hopewell
2013-04-01

Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer

Christina Curtis, Anne-Lise Børresen-Dale, Hans Kristian Moen Vollan, Erich Huang, Lara M. Mangravite, Vessela Kristensen, Hege G. Russnes, Carlos Caldas, Gustavo Stolovitzky, Stephen Friend, Justin Guinney, Michael Kellen, Adam A Margolin, Samuel Aparicio, Erhan Bilal, Bruce Hoff, Thea Norman, Oscar M Rueda, Lars Ottestad
2013-05-01

Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge

Niek de Vries, Leonid Padyukov, Anne Barton, Lars Klareskog, Lara M. Mangravite, Henk-Jan Guchelaar, Peter K. Gregersen, Tom Huizinga, Xavier Mariette, Gustavo Stolovitzky, Stephen Friend, Robert M Plenge, Eli A Stahl, Marieke J H Coenen, Jeffrey D Greenberg, S Louis Bridges, Larry Moreland
2013-08-01

Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs

Lara M. Mangravite

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Lara M. Mangravite

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