Inventaire - your friends and communities are your best library

Directed evolution of enzyme catalysts

Author

Frances Arnold

Published in: Trends in Biotechnology

Date of publication: December 1997

Language: English

Main subject: directed evolution, molecular evolution

Bibliographic databases:

Cites articles 42

Date

Title

Authors

December 1, 1986

Proteases of enhanced stability: characterization of a thermostable variant of subtilisin
January 1, 1986

A simple and efficient procedure for saturation mutagenesis using mixed oligodeoxynucleotides
January 1, 1986

Cloning of random-sequence oligodeoxynucleotides
February 1, 1986

Isolation of a thermostable enzyme variant by cloning and selection in a thermophile
July 1, 1988

Combinatorial cassette mutagenesis as a probe of the informational content of protein sequences
August 1, 1989

Protein evolution on rugged landscapes
September 1, 1990

Additivity of mutational effects in proteins
December 1, 1992

Hyperthermostable variants of a highly thermostable alpha-amylase
June 1, 1992

From adenylate cyclase to guanylate cyclase. Mutational analysis of a change in substrate specificity
December 1, 1993

Development of an in vivo method to identify mutants of phage T4 lysozyme of enhanced thermostability
June 1, 1993

Tuning the activity of an enzyme for unusual environments: sequential random mutagenesis of subtilisin E for catalysis in dimethylformamide
August 4, 1994

Rapid evolution of a protein in vitro by DNA shuffling
June 1, 1994

Polymerase chain reaction-based random mutagenesis: production and characterization of thermostable mutants of Zymomonas mobilis alcohol dehydrogenase-2.
October 1, 1994

A novel strategy for stabilization of Escherichia coli ribonuclease HI involving a screen for an intragenic suppressor of carboxyl-terminal deletions,A novel strategy for stabilization of Escherichia coli ribonuclease HI involving a screen for an intragenic suppressor of carboxyl-terminal deletions.
July 1, 1995

Directed evolution of a subtilisin with calcium-independent stability,Directed Evolution of a Subtilisin with Calcium-Independent Stability
June 1, 1995

Increase in thermostability of recombinant barley beta-amylase by random mutagenesis
June 1, 1995

Screening of stable proteins in an extreme thermophile, Thermus thermophilus
September 1, 1995

A mutant T7 RNA polymerase as a DNA polymerase
July 1, 1995

Glutathione transferases with novel active sites isolated by phage display from a library of random mutants,Glutathione Transferases with Novel Active Sites Isolated by Phage Display from a Library of Random Mutants
March 1, 1995

Context dependence of phenotype prediction and diversity in combinatorial mutagenesis
August 1, 1995

Random recombination of antibody single chain Fv sequences after fragmentation with DNasel in the presence of Mn2+
August 1, 1995

Forced evolution of glutathione S-transferase to create a more efficient drug detoxication enzyme
October 1, 1996

Tolerance of different proteins for amino acid diversity
December 1996

Directed evolution: Creating biocatalysts for the future
January 1, 1996

Directed evolution of subtilisin E in Bacillus subtilis to enhance total activity in aqueous dimethylformamide
April 1, 1996

Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solvents
February 1, 1996

Further stabilization of 3-isopropylmalate dehydrogenase of an extreme thermophile, Thermus thermophilus, by a suppressor mutation method
November 1, 1996

Substitutions of Ser for Asn-163 and Pro for Leu-264 are important for stabilization of lipase from Pseudomonas aeruginosa
November 1, 1996

Guided evolution of enzymes with new substrate specificities
March 1, 1996

Selection of Streptomyces griseus protease B mutants with desired alterations in primary specificity using a library screening strategy
April 1, 1996

Conversion from farnesyl diphosphate synthase to geranylgeranyl diphosphate synthase by random chemical mutagenesis

,
June 1, 1996

Hydrolytic antibodies: variations on a theme

Article -

Welcome to inventaire

The library of your friends and communities

Jsi offline