Inventaire - your friends and communities are your best library

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

published in: Nature

date of publication: 2004-10-14

language: English

Bibliographic databases:

Cites articles 45

Date

Title

Authors

1988-08-01

Differential loss of striatal projection neurons in Huntington disease
1995-12-01

Preferential loss of preproenkephalin versus preprotachykinin neurons from the striatum of Huntington's disease patients
1996-08-01

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
1996-11-01

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

,
1996-01-01

Differential expression of normal and mutant Huntington's disease gene alleles
1997-08-01

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

, ,
1997-09-01

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
1997-12-01

Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse
1997-12-01

Intranuclear neuronal inclusions: a common pathogenic mechanism for glutamine-repeat neurodegenerative diseases?
1997-08-01

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

, , ,
1997-11-01

CREB: a major mediator of neuronal neurotrophin responses
1998-04-01

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

, ,
1998-04-01

Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length
1998-10-01

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions

,
1998-10-01

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice

, ,
1998-10-01

Nuclear inclusions in glutamine repeat disorders: are they pernicious, coincidental, or beneficial?
1998-01-01

Molecular genetics of Huntington's disease
1999-12-01

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

, ,
1999-09-01

Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells
1999-04-01

Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology
1999-06-01

Evidence for a recruitment and sequestration mechanism in Huntington's disease
1999-02-01

Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition
1999-08-01

Nuclear targeting of mutant Huntingtin increases toxicity
2000-03-01

Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease
2000-07-01

A one-hit model of cell death in inherited neuronal degenerations
2000-02-01

Green fluorescent protein as a quantitative tool

,
2001-05-25

Impairment of the ubiquitin-proteasome system by protein aggregation
2001-08-01

Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity
2001-07-01

Cause of neural death in neurodegenerative diseases attributable to expansion of glutamine repeats
2001-10-01

Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis
2001-03-01

Tissue-specific proteolysis of Huntingtin (htt) in human brain: evidence of enhanced levels of N- and C-terminal htt fragments in Huntington's disease striatum
2001-02-01

Green fluorescent protein as a novel tool to measure apoptosis and necrosis

Article -

Welcome to Inventaire

the library of your friends and communities

learn more