Obi Griffith

country of citizenship: Canada

educated at: University of British Columbia

occupation: oncologist

official website: obigriffith.org

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Articles 126

Date

Title

Authors

2023-03-08

Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy

Cristina Puig-Saus, Huiming Xia, Jonathan Hoover, Shahab Chizari, Bartosz Chmielowski, Alena Gros, Obi Griffith, Malachi Griffith, James R. Heath, Antoni Ribas
2021-01-01

Correction: Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus-unrelated Head and Neck Cancer: A Multicenter, Phase II Trial

Obi Griffith, Malachi Griffith, Zachary L Skidmore, Erica K Barnell
2021-02-05

Yap1 Mediates Trametinib Resistance in Head and Neck Squamous Cell Carcinomas

Katie M Campbell, Zachary L Skidmore, Erica K Barnell, Malachi Griffith, Obi Griffith
2021-11-10

The GA4GH Variation Representation Specification: A computational framework for variation representation and federated identification

Alex H Wagner, Michael Baudis, Daniel L Cameron, Melissa S. Cline, Malachi Griffith, Obi Griffith, Sarah E. Hunt, Kirill Yu Tsukanov, Melissa Konopko, Robert R Freimuth, Reece K Hart
2020-03-17

Wikidata as a knowledge graph for the life sciences

Andra Waagmeester, Gregory Stupp, Sebastian Burgstaller-Muehlbacher, Benjamin M. Good, Malachi Griffith, Obi Griffith, Kristina Hanspers, Henning Hermjakob, Toby Hudson, Kevin Hybiske, Sarah M Keating, Magnus Manske, Michael Mayers, Daniel Mietchen, Elvira Mitraka, Alexander R. Pico, Timothy Elliott Putman, Anders Riutta, Núria Queralt Rosinach, Lynn Schriml, Thomas Shafee, Denise Slenter, Ralf Stephan, Katherine Thornton, Ginger Tsueng, Roger Tu, Sabah Ul-Hasan, Egon Willighagen, Chunlei Wu, Andrew I. Su
2020-03-01

CIViCpy: A Python Software Development and Analysis Toolkit for the CIViC Knowledgebase

Obi Griffith, Arpad M Danos, Malachi Griffith, Alex H Wagner, Susanna Kiwala, Kilannin Krysiak, Erica K Barnell, Joshua F. McMichael, Adam C. Coffman
2020-04-03

A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer

Alex H Wagner, Brian Walsh, Dmitriy Sonkin, Kilannin Krysiak, Jianjiong Gao, Jeremy L. Warner, Damian T Rieke, Tero Aittokallio, Robert R Freimuth, Melissa Haendel, Jacques S Beckmann, Susan Mockus, Malachi Griffith, Obi Griffith, Lynn Schriml, Adam A Margolin, Jeremy Goecks, Julie A. McMurry
2020-01-06

pVACtools: A Computational Toolkit to Identify and Visualize Cancer Neoantigens

Jasreet Hundal, Susanna Kiwala, Huiming Xia, Sidi Zhao, Yang-Yang Feng, Aaron P Graubert, Megan Neveau, Obi Griffith, Elaine Mardis, Joshua F. McMichael
2020-07-14

Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus-Unrelated Head and Neck Cancer: A Multicenter, Phase 2 Trial

Katie M Campbell, Zachary L Skidmore, Brian Nussenbaum, Randal C Paniello, Patrik Pipkorn, Erica K Barnell, Iulia Cirlan, Trevor J Pugh, Jonathan D Schoenfeld, Evisa Gjini, Ian S Hagemann, Jay F Piccirillo, Malachi Griffith, Obi Griffith
2020-07-01

Collaborative, Multidisciplinary Evaluation of Cancer Variants Through Virtual Molecular Tumor Boards Informs Local Clinical Practices

Peter K. Rogan, Obi Griffith, Malachi Griffith, Simina M. Boca, Alex H Wagner
2020-10-10

Splicing factor SF3B1 promotes endometrial cancer progression via regulating KSR2 RNA maturation

Malachi Griffith, Ramakrishna Kommagani, Obi Griffith
2020-11-25

Integration of the Drug-Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts

Obi Griffith, Malachi Griffith, Susanna Kiwala, Alex H Wagner, Joshua F. McMichael, Adam C. Coffman
2019-10-01

Open-Sourced CIViC Annotation Pipeline to Identify and Annotate Clinically Relevant Variants Using Single-Molecule Molecular Inversion Probes

Obi Griffith, Arpad M Danos, Damian T Rieke, Malachi Griffith, Zachary L Skidmore, Kilannin Krysiak, Erica K Barnell, Lana M. Sheta
2019-11-04

Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens

Obi Griffith, Elaine Mardis, Malachi Griffith, Zachary L Skidmore
2019-11-16

Reply

Erica K Barnell, Obi Griffith, Malachi Griffith
2019-11-29

Standard operating procedure for curation and clinical interpretation of variants in cancer

Erica K Barnell, Susanna Kiwala, Dmitriy Sonkin, Raymond H Kim, Obi Griffith, Arpad M Danos, Malachi Griffith, Alex H Wagner, Kilannin Krysiak, Joshua F. McMichael, Lana M. Sheta, Adam C. Coffman
2019-12-03

Text-mining clinically relevant cancer biomarkers for curation into the CIViC database

Steven Jones, Obi Griffith, Arpad M Danos, Malachi Griffith, Kilannin Krysiak
2019-11-02

A virome sequencing approach to feline oral squamous cell carcinoma to evaluate viral causative factors

Obi Griffith, Zachary L Skidmore, Kristine M Wylie
2019-05-30

Noninvasive Detection of High-Risk Adenomas Using Stool-Derived Eukaryotic RNA Sequences as Biomarkers

Obi Griffith, Malachi Griffith, Erica K Barnell
2019-08-01

A Spontaneous Aggressive ERα+ Mammary Tumor Model Is Driven by Kras Activation

Obi Griffith, Malachi Griffith, Zachary L Skidmore, Kilannin Krysiak, Erica K Barnell
2019-08-16

Targeting the Mevalonate Pathway to Overcome Acquired Anti-HER2 Treatment Resistance in Breast Cancer

Vidyalakshmi Sethunath, Carmine De Angelis, Tao Wang, Obi Griffith, Laura M Heiser, Susan Hilsenbeck, Rachel Schiff, Joe W Gray
2019-08-28

Best practices for bioinformatic characterization of neoantigens for clinical utility

Malachi Griffith, Obi Griffith
2019-10-01

Rapid progression of adult T-cell leukemia/lymphoma as tumor-infiltrating Tregs after PD-1 blockade

Obi Griffith, Malachi Griffith, Zachary L Skidmore, Thomas Waldmann
2018-06-01

A case of acute myeloid leukemia with promyelocytic features characterized by expression of a novel RARG-CPSF6 fusion

Obi Griffith, Malachi Griffith, Zachary L Skidmore
2018-12-03

Accounting for proximal variants improves neoantigen prediction

Jasreet Hundal, Susanna Kiwala, Yang-Yang Feng, Obi Griffith, Malachi Griffith, Elaine Mardis
2018-11-05

A deep learning approach to automate refinement of somatic variant calling from cancer sequencing data

Benjamin J Ainscough, Erica K Barnell, Katie M Campbell, Alex H Wagner, Todd A Fehniger, Malachi Griffith, Obi Griffith, Elaine Mardis
2018-09-17

Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer

Alex H Wagner, Kilannin Krysiak, Avinash Ramu, Ismail Can, Trudy G Oliver, Obi Griffith, Elaine Mardis, Malachi Griffith, Zachary L Skidmore
2018-09-04

The prognostic effects of somatic mutations in ER-positive breast cancer

Katie M Campbell, Kilannin Krysiak, Benjamin J Ainscough, Jingqin Luo, Obi Griffith, Catrina Fronick, Mitch Dowsett, Elaine Mardis, Malachi Griffith, Zachary L Skidmore
2018-11-14

Author Correction: The prognostic effects of somatic mutations in ER-positive breast cancer

Obi Griffith, Kilannin Krysiak, Benjamin J Ainscough, Sherri R Davies, David E Larson, Elaine Mardis, Malachi Griffith, Zachary L Skidmore
2018-02-16

Standard operating procedure for somatic variant refinement of tumor sequencing data

Obi Griffith, Malachi Griffith, Alex H Wagner, Zachary L Skidmore, Katie M Campbell, Kilannin Krysiak, Erica K Barnell
2018-08-01

Oral Cavity Squamous Cell Carcinoma Xenografts Retain Complex Genotypes and Intertumor Molecular Heterogeneity.

Katie M Campbell, Erica K Barnell, Elaine Mardis, Obi Griffith, Malachi Griffith, Zachary L Skidmore
2018-11-01

Adapting crowdsourced clinical cancer curation in CIViC to the ClinGen minimum variant level data community-driven standards

Arpad M Danos, Alex H Wagner, Dmitriy Sonkin, Simina M. Boca, Erica K Barnell, Susanna Kiwala, Malachi Griffith, Obi Griffith, Subha Madhavan, Kilannin Krysiak, Joshua F. McMichael, Adam C. Coffman

Human - wd:Q30503239

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