The Journal of Clinical Investigation is a semi-monthly peer-reviewed medical journal covering biomedical research. It was established in 1924 and is published by the American Society for Clinical Investigation. Articles focus on the mechanisms of disease, with an emphasis on basic research, early-stage clinical studies in humans, and new research tools and techniques. The journal also publishes reviews in edited series or as stand-alone articles, commentaries on research, editorials, and feature items. The editor-in-chief is Elizabeth M. McNally (Northwestern University). Source: Wikipedia (en)