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How the protease thrombin talks to cells

Published in: Proceedings of the National Academy of Sciences of the United States of America

Date of publication: September 1, 1999

Language: English

Bibliographic databases:

Cites articles 66

Date

Title

Authors

December 1, 1967

Actions of thrombin and other coagulant and proteolytic enzymes on blood platelets,Actions of Thrombin and Other Coagulant and Proteolytic Enzymes on Blood Platelets
January 1, 1975

Mitogenic activity of blood components. I. Thrombin and prothrombin
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The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding. The refined crystal structures of the bovine trypsinogen-pancreatic trypsin inhibitor complex and of its ternary complex with Ile-Val at 1.9 A resolution
July 1, 1986

Thrombin stimulates c-sis gene expression in microvascular endothelial cells
May 15, 1989

Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140
June 1, 1990

beta-Arrestin: a protein that regulates beta-adrenergic receptor function

, ,
October 1, 1991

Domains specifying thrombin–receptor interaction
March 22, 1991

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
August 1, 1991

cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2+ mobilization
September 1, 1991

The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity
July 1, 1992

Structure and function of the human platelet thrombin receptor. Studies using monoclonal antibodies directed against a defined domain within the receptor N terminus
July 1, 1992

Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function
April 1, 1992

Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation
March 1, 1992

Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides
February 1, 1992

"Mirror image" antagonists of thrombin-induced platelet activation based on thrombin receptor structure
December 1, 1992

Thrombin receptor activating peptides: importance of the N-terminal serine and its ionization state as judged by pH dependence, nuclear magnetic resonance spectroscopy, and cleavage by aminopeptidase M
January 1, 1993

Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor

, ,
May 1, 1993

Kinetics of thrombin receptor cleavage on intact cells. Relation to signaling
January 1, 1993

Beta-adrenergic receptor sequestration. A potential mechanism of receptor resensitization
June 1, 1993

Internalization and recycling of activated thrombin receptors
January 1, 1994

Cathepsin G and thrombin: evidence for two different platelet receptors
January 1, 1994

Disparate temporal expression of the prothrombin and thrombin receptor genes during mouse development
May 1, 1994

Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin
April 1, 1994

Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surface
March 22, 1994

Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes
November 1, 1994

Intracellular targeting and trafficking of thrombin receptors. A novel mechanism for resensitization of a G protein-coupled receptor
June 1, 1994

Alpha-thrombin and trypsin use different receptors to stimulate arachidonic acid metabolism
September 27, 1994

Molecular cloning of a potential proteinase activated receptor
January 1, 1994

Inhibition of thrombin receptor signaling by a G-protein coupled receptor kinase. Functional specificity among G-protein coupled receptor kinases
June 1, 1994

Thrombin receptor activation. Confirmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode
September 1, 1994

Regulation of vascular endothelial barrier function
October 1, 1994

Species variability in platelet and other cellular responsiveness to thrombin receptor-derived peptides

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