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Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization

Published in: Journal of Clinical Investigation

Date of publication: December 1, 1993

Language: English

Main subject: plasminogen

Bibliographic databases:

Cites articles 26

Date

Title

Authors

October 1, 1976

Plasminogen activator in early embryogenesis: enzyme production by trophoblast and parietal endoderm
January 1, 1977

Implantation. The role of proteinases, and blockage of implantation by proteinase inhibitors
July 1, 1984

Evidence for the occurrence of a fast-acting inhibitor for tissue-type plasminogen activator in human plasma
June 1985

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium
September 1, 1985

Endothelial cells produce a latent inhibitor of plasminogen activators that can be activated by denaturants
October 1, 1986

Endothelial plasminogen activator inhibitor (PAI): a new member of the Serpin gene family
April 1987

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction,Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

,
November 24, 1988

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
January 1, 1989

Suppression of ovulation rate by antibodies to tissue-type plasminogen activator and alpha 2-antiplasmin
June 1, 1989

Efficient oligonucleotide-directed construction of mutations in expression vectors by the gapped duplex DNA method using alternating selectable markers.
January 1, 1989

Type 1 plasminogen activator inhibitor
July 1, 1989

Plasminogen activator inhibitor types 1 and 2 in human trophoblasts. PAI-1 is an immunocytochemical marker of invading trophoblasts
March 1, 1990

The c-myc-regulated gene mrl encodes plasminogen activator inhibitor 1
April 1, 1990

Urokinase-dependent cell surface proteolysis and cancer
December 1, 1990

Mechanisms of trophoblast invasiveness and their control: the role of proteases and protease inhibitors
December 1, 1990

Growth factor control of extracellular proteolysis

,
June 1, 1991

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
August 11, 1991

Simplified mammalian DNA isolation procedure
October 1, 1991

The plasminogen activator/plasmin system
July 1, 1991

Hormone regulation of tissue-type plasminogen activator gene expression and plasminogen activator-mediated proteolysis
December 1, 1991

Basic and clinical aspects of fibrinolysis and thrombolysis
June 1, 1992

Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs
October 1, 1992

Purification and characterization of active and latent forms of recombinant plasminogen activator inhibitor 1 produced in Escherichia coli
July 1, 1992

Reactivated recombinant plasminogen activator inhibitor-1 (rPAI-1) effectively prevents thrombolysis in vivo
February 1, 1993

Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation
December 1, 1993

Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis

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