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Mathematical analysis of activation thresholds in enzyme-catalyzed positive feedbacks: application to the feedbacks of blood coagulation

Published in: Proceedings of the National Academy of Sciences of the United States of America

Date of publication: September 1, 1995

Language: English

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Cites articles 15

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Impulses and Physiological States in Theoretical Models of Nerve Membrane
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The importance of activation of antihemophilic globulin and proaccelerin by traces of thrombin in the generation of intrinsic prothrombinase activity
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Autoactivation of human Hageman factor. Demonstration utilizing a synthetic substrate
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Role of human factor VIII in factor X activation
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Stabilization of thrombin-activated porcine factor VIII:C by factor IXa phospholipid
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Detection of factor X activation in humans
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In situ-generated thrombin is the only enzyme that effectively activates factor VIII and factor V in thromboplastin-activated plasma
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Interaction of feedback control and product inhibition in the activation of factor X by factors IXa and VIII.
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Mathematical analysis of a proteolytic positive-feedback loop: dependence of lag time and enzyme yields on the initial conditions and kinetic parameters
October 1, 1993

Factor VII autoactivation proceeds via interaction of distinct protease-cofactor and zymogen-cofactor complexes. Implications of a two-dimensional enzyme kinetic mechanism
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A model for the tissue factor pathway to thrombin. II. A mathematical simulation
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Ventralizing signal determined by protease activation in Drosophila embryogenesis
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A model for the tissue factor pathway to thrombin. I. An empirical study

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