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Sleeping beauty transposition: biology and applications for molecular therapy

Author

Zoltán Ivics

1964 -

Zsuzsanna Izsvák

1961 -

Published in: Molecular Therapy

Date of publication: February 1, 2004

Bibliographic databases:

Cites articles 71

Date

Title

Authors

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Insertional mutagenesis of the Drosophila genome with single P elements
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Evidence for Drosophila P element transposase activity in mammalian cells and yeast
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Transcriptionally active genome regions are preferred targets for retrovirus integration
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Characterization of two hypertransposing Tn5 mutants
August 1, 1993

Dominant transposition-deficient mutants of maize Activator (Ac) transposase
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Characterization of the Caenorhabditis elegans Tc1 transposase in vivo and in vitro
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A proposed superfamily of transposase genes: transposon-like elements in ciliated protozoa and a common "D35E" motif
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The mechanism of transposition of Tc3 in C. elegans

,
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Target site choice of the related transposable elements Tc1 and Tc3 of Caenorhabditis elegans
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Requirement of RNA polymerase III transcription factors for in vitro position-specific integration of a retroviruslike element
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Mapping domains of retroviral integrase responsible for viral DNA specificity and target site selection by analysis of chimeras between human immunodeficiency virus type 1 and visna virus integrases
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Identification of functional domains and evolution of Tc1-like transposable elements
February 20, 1996

Tiggers and DNA transposon fossils in the human genome
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The Saccharomyces retrotransposon Ty5 integrates preferentially into regions of silent chromatin at the telomeres and mating loci
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Autoregulation of mariner transposase activity by overproduction and dominant-negative complementation.
May 1, 1997

What restricts the activity of mariner-like transposable elements.
November 14, 1997

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells
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Factors responsible for target site selection in Tn10 transposition: a role for the DDE motif in target DNA capture
December 1, 1997

Molecular evolution of the second ancient human mariner transposon, Hsmar2, illustrates patterns of neutral evolution in the human genome lineage
December 31, 1997

Molecular evolution of an ancient mariner transposon, Hsmar1, in the human genome,Molecular evolution of an ancient mariner transposon, Hsmarl, in the human genome
October 1, 1997

High mobility group chromosomal protein 1 binds to the adeno-associated virus replication protein (Rep) and promotes Rep-mediated site-specific cleavage of DNA, ATPase activity and transcriptional repression
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Target site selection in transposition
January 1, 1998

Transposition of the nematode Caenorhabditis elegans Tc3 element in the zebrafish Danio rerio.
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Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells
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Repeat-induced gene silencing in mammals
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An estimated frequency of endogenous insertional mutations in humans
July 1999

Alu repeats and human disease
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Resident aliens: the Tc1/mariner superfamily of transposable elements
August 1, 1999

Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins
January 1, 1999

A mechanism for Tn5 inhibition. carboxyl-terminal dimerization
November 1, 1999

Integrating adenovirus-adeno-associated virus hybrid vectors devoid of all viral genes

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