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Deregulation of the Egfr/Ras signaling pathway induces age-related brain degeneration in the Drosophila mutant vap.

Автор

Doris Kretzschmar

опубликовано в: Молекулярная биология клетки

дата публикации: 2003-01-01

главная тема: дрозофилы, Ras GTPase activating protein 1 Dmel_CG6721

Bibliographic databases:

Cites articles 57

Дата

Заголовок

Авторы

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The use of lead citrate at high pH as an electron-opaque stain in electron microscopy
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Glial membrane specializations and the compartmentalization of the lamina ganglionaris of the housefly compound eye.
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The fine structure of neuroglia in the lamina ganglionaris of the housefly, Musca domestica L.
1986-06-01

Tissue localization of Drosophila melanogaster ras transcripts during development
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Alternative 5' exons and tissue-specific expression of the Drosophila EGF receptor homolog transcripts
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The locus elav of Drosophila melanogaster is expressed in neurons at all developmental stages.
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P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila
1989-12-01

Coordinately and differentially mutable activities of torpedo, the Drosophila melanogaster homolog of the vertebrate EGF receptor gene
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Developmental cell death: morphological diversity and multiple mechanisms
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rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster
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Characterization and spatial distribution of the ELAV protein duringDrosophila melanogaster development
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mip causes hyperinnervation of a retinotopic map in drosophila by excessive recruitment of R7 photoreceptor cells
1992-03-01

A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase
1993-04-01

A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.
1993-04-01

An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro
1993-05-06

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras
1993-10-01

Programmed cell death and the control of cell survival: lessons from the nervous system
1993-06

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
1993-06-01

The Drosophila rhomboid gene mediates the localized formation of wing veins and interacts genetically with components of the EGF-R signaling pathway
1993-05-01

Multiple extracellular signals are required for long-term oligodendrocyte survival
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Multiple Ras functions can contribute to mammalian cell transformation
1995-06-01

Biochemical and genetic analysis of the Drk SH2/SH3 adaptor protein of Drosophila
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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
1995-10-26

Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein
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The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway
1996-11-01

The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm
1996-10-01

A modular misexpression screen in Drosophila detecting tissue-specific phenotypes
1996-09-01

Expression of Drosophila mushroom body mutations in alternative genetic backgrounds: a case study of the mushroom body miniature gene (mbm)
1996-06-01

Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase
1997-10-01

The swiss cheese mutant causes glial hyperwrapping and brain degeneration in Drosophila
1997-04-01

Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap

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