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When reverse genetics meets physiology: the use of site-specific recombinases in mice

Author

Emilio Casanova

1955 -

François Tronche

Published in: FEBS Letters

Date of publication: October 1, 2002

Language: English

Main subject: physiology

Bibliographic databases:

Cites articles 67

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Site-specific recombinational circularization of bacteriophage P1 DNA
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Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1
July 15, 1992

Targeted oncogene activation by site-specific recombination in transgenic mice
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Tissue- and site-specific DNA recombination in transgenic mice
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Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
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A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination
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Inducible gene targeting in mice
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Inducible site-directed recombination in mouse embryonic stem cells
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Variegated gene expression in mice
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Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome,Homologous recombination based modification in Esherichia coli and germline transmission in transgenic mice of a bacterial artificial chromsome
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Targeted integration of DNA using mutant lox sites in embryonic stem cells
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The Kw recombinase, an integrase from Kluyveromyces waltii,The Kw Recombinase, an Integrase from Kluyveromyces Waltii
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Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse
January 1, 1998

Similarities and differences among 105 members of the Int family of site-specific recombinases
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Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles

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Improved properties of FLP recombinase evolved by cycling mutagenesis

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Structure and mechanism in site-specific recombination
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Generalized lacZ expression with the ROSA26 Cre reporter strain
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Quantitative comparison of DNA looping in vitro and in vivo: chromatin increases effective DNA flexibility at short distances
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Inducible site-specific recombination in the brain
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Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases
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Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety
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Engineering a mouse balancer chromosome
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Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange

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