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A comprehensive model for the humoral coagulation network in humans.

Author

Stephen Duffull

1964 -

Published in: Clinical Pharmacology & Therapeutics

Date of publication: June 10, 2009

Language: English

Bibliographic databases:

Cites articles 35

Date

Title

Authors

February 1, 1981

The molecular-weight dependence of the rate-enhancing effect of heparin on the inhibition of thrombin, factor Xa, factor IXa, factor XIa, factor XIIa and kallikrein by antithrombin
December 1, 1983

Cyclic interconversion of vitamin K1 and vitamin K1 2,3-epoxide in man.
November 1, 1986

Clinical pharmacokinetics and pharmacodynamics of warfarin. Understanding the dose-effect relationship
January 1, 1988

The relationship between inhibition of vitamin K1 2,3-epoxide reductase and reduction of clotting factor activity with warfarin
September 1, 1988

Comprehensive clinical and statistical analysis of hemophilia in Korea
January 1, 1989

A mathematical model of the kinetics of blood coagulation
January 1, 1989

Effect of heparin on the inhibition of the contact system enzymes
February 1, 1995

Coagulopathy following bites by the Papuan taipan (Oxyuranus scutellatus canni)

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December 1, 1996

A mathematical model for the spatio-temporal dynamics of intrinsic pathway of blood coagulation. II. Results
July 1, 1996

Plasma concentrations of dihydro-vitamin K1 following dietary intake of a hydrogenated vitamin K1-rich vegetable oil
December 1, 1996

Assessment of vitamin K status in human subjects administered "minidose" warfarin
January 1, 1996

Elimination half-life of vitamin K1 in neonates is longer than is generally assumed: implications for the prophylaxis of haemorrhaghic disease of the newborn
April 1, 1997

Relationships between dietary intakes and fasting plasma concentrations of fat-soluble vitamins in humans

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March 1, 1998

Mathematical model for the blood coagulation prothrombin time test,Mathematical Model for the Blood Coagulation Prothrombin Time Test
March 1, 1998

Characteristics of indirect pharmacodynamic models and applications to clinical drug responses
May 1, 1999

A model describing the inactivation of factor Va by APC: bond cleavage, fragment dissociation, and product inhibition
1999

Biochemistry and Physiology of Blood Coagulation
February 1, 2001

Analysis of the activated partial thromboplastin time test using mathematical modeling
September 1, 2002

Platelets and thrombin generation
January 1, 2003

The dynamics of thrombin formation
July 1, 2003

Development of a dosing strategy for enoxaparin in obese patients
February 1, 2003

A Bayesian method based on clotting factor activity for the prediction of maintenance warfarin dosage regimens
September 1, 2004

The pharmacology and management of the vitamin K antagonists: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
September 1, 2004

Heparin and low-molecular-weight heparin: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
May 1, 2004

The kinetic model and simulation of blood coagulation--the kinetic influence of activated protein C.
March 1, 2005

A kinetic model for simulation of blood coagulation and inhibition in the intrinsic path
January 1, 2005

Mathematical modeling and computer simulation in blood coagulation
September 19, 2006

Pharmacogenetics of warfarin: current status and future challenges

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February 2006

Tissue factor pathway inhibitor: structure, biology and involvement in disease
February 23, 2006

Models of blood coagulation
May 1, 2007

Theories of blood coagulation
February 12, 2007

The use of mechanistic DM-PK-PD modelling to assess the power of pharmacogenetic studies -CYP2C9 and warfarin as an example

Article -

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