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Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts

Author

Joseph L. Goldstein

1940 -

Published in: Proceedings of the National Academy of Sciences of the United States of America

Date of publication: September 1, 1976

Language: English

Main subject: hypercholesterolemia, homozygous familial hypercholesterolemia, drug receptors, homozygosity

Bibliographic databases:

Cites articles 22

Date

Title

Authors

November 1, 1951

Protein measurement with the Folin phenol reagent

, , ,
November 1, 1968

Electrophoretic separation of plasma lipoproteins in agarose gel.
March 1, 1972

Use of cationized ferritin as a label of negative charges on cell surfaces
January 1, 1973

Neuraminidase, sialic acids, and cell interactions
November 1, 1974

Esterification of low density lipoprotein cholesterol in human fibroblasts and its absence in homozygous familial hypercholesterolemia
August 1, 1974

Binding and degradation of low density lipoproteins by cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia
March 1974

Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity
February 1, 1974

Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia
November 1, 1974

Incorporation of lipid vesicles by mammalian cells provides a potential method for modifying cell behaviour
November 1, 1974

Suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol
January 1, 1975

A general method for the introduction of enzymes, by means of immunoglobulin-coated liposomes, into lysosomes of deficient cells
September 1, 1975

The distribution and mobility of anionic sites on the surfaces of baby hamster kidney cells
August 1, 1975

Receptor-dependent hydrolysis of cholesteryl esters contained in plasma low density lipoprotein
March 1, 1975

Genetic heterogeneity in familial hypercholesterolemia: evidence for two different mutations affecting functions of low-density lipoprotein receptor
November 1, 1975

Regulation of the activity of the low density lipoprotein receptor in human fibroblasts
November 1, 1975

Role of lysosomal acid lipase in the metabolism of plasma low density lipoprotein. Observations in cultured fibroblasts from a patient with cholesteryl ester storage disease
October 1, 1975

Thermal Transitions in Human Plasma Low Density Lipoproteins
October 1, 1975

Inhibition of proteolytic degradation of low density lipoprotein in human fibroblasts by chloroquine, concanavalin A, and Triton WR 1339
May 1, 1975

Cholesterol ester formation in cultured human fibroblasts. Stimulation by oxygenated sterols
January 1, 1976

Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans
June 1, 1976

Familial hypercholesterolemia: A genetic defect in the low-density lipoprotein receptor

,
January 16, 1976

Receptor-mediated control of cholesterol metabolism

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