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Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells

Author

Rudolf Jaenisch

1942 -

Published in: Proceedings of the National Academy of Sciences of the United States of America

Date of publication: March 1, 1994

Language: English

Bibliographic databases:

Cites articles 19

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Targetted correction of a mutant HPRT gene in mouse embryonic stem cells
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Production of chimaeric mice containing embryonic stem (ES) cells carrying a homoeobox Hox 1.1 allele mutated by homologous recombination
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Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein
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Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells
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Target frequency and integration pattern for insertion and replacement vectors in embryonic stem cells
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Cotransformation and gene targeting in mouse embryonic stem cells
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The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos
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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
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Investigation of coelectroporation as a method for introducing small mutations into embryonic stem cells
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Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development

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Site-directed point mutations in embryonic stem cells: a gene-targeting tag-and-exchange strategy

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