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Neuronal apoptosis in neurodegenerative diseases: from basic research to clinical application

published in: Neurodegenerative Diseases

date of publication: 2004-01-01

main subject: neurodegeneration

Bibliographic databases:

Cites articles 57

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Title

Authors

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Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics,Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics
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Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients
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Trophic factors and neuronal survival
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BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease
1995-01-13

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy
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DNA end labeling (TUNEL) in Huntington's disease and other neuropathological conditions,DNA End Labeling (TUNEL) in Huntington's Disease and Other Neuropathological Conditions
1996-10-18

Human ICE/CED-3 protease nomenclature
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Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
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NMR structure of the death domain of the p75 neurotrophin receptor
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Cytochrome c: can't live with it--can't live without it.
1997-11-14

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
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PI3K: downstream AKTion blocks apoptosis
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Expression of c-Jun in dopaminergic neurons of the substantia nigra in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice
1997-05

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain
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Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis
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Bcl-2 family proteins
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Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast
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Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease
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Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: relevance to Parkinson's disease
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Expression of polyglutamine-expanded Huntingtin activates the SEK1-JNK pathway and induces apoptosis in a hippocampal neuronal cell line
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Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

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Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD
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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
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Parkinson's disease and the U.S. health care system
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Dopaminergic neurons degenerate by apoptosis in Parkinson's disease

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Cell death and apoptosis regulating proteins in Parkinson's disease--a cautionary note
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Apoptosis in neurodegenerative disorders.

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