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Mitochondria in amyotrophic lateral sclerosis: a trigger and a target

published in: Neurodegenerative Diseases

date of publication: 2004-01-01

main subject: amyotrofická laterální skleróza

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Cites articles 65

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

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1993-04-01

Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?,Do defecs in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?
1993-08-01

ALS, SOD and peroxynitrite
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An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

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1996-10-01

Amyotrophic lateral sclerosis: oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes
1996-02-01

Ultrastructural study of synapses in the anterior horn neurons of patients with amyotrophic lateral sclerosis
1997-09-01

Expression of a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis induces mitochondrial alteration and increase of cytosolic Ca2+ concentration in transfected neuroblastoma SH-SY5Y cells
1997-07-01

Inhibition of ICE slows ALS in mice
1998-09-01

Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1
1998-01-01

Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease

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1998-12-01

Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase
1998-07-01

Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects
1999-10-01

Visualization of defective mitochondrial function in skeletal muscle fibers of patients with sporadic amyotrophic lateral sclerosis
1999-12-01

Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis
1999-03-01

Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis

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Acute decrease in net glutamate uptake during energy deprivation
2000-12-01

Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis
2000-07-01

Cytochrome c nitration by peroxynitrite.
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Nutritional assessment and survival in ALS patients
2001-10-01

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

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The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

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Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity

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Selective changes in mitochondria respiratory properties in oxidative or glycolytic muscle fibers isolated from G93AhumanSOD1 transgenic mice
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Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu,Zn-SOD in mitochondria
2001-01-15

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2001-12-01

Mitochondrial tyrosine nitration precedes chronic allograft nephropathy
2001-03-01

Intrathecal cyclosporin prolongs survival of late-stage ALS mice
2001-04-01

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Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport

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A quantitative histochemical assay for activities of mitochondrial electron transport chain complexes in mouse spinal cord sections
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Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis

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