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Urokinase-type plasminogen activator is effective in fibrin clearance in the absence of its receptor or tissue-type plasminogen activator

Author

Thomas H. Bugge

Published in: Proceedings of the National Academy of Sciences of the United States of America

Date of publication: June 1, 1996

Language: English

Main subject: plasminogen

Bibliographic databases:

Cites articles 41

Date

Title

Authors

April 1, 1974

Secretion of plasminogen activator by stimulated macrophages
July 1, 1977

Macrophage plasminogen activator: induction by concanavalin A and phorbol myristate acetate
October 1, 1982

Nucleotide sequence and exact localization of the neomycin phosphotransferase gene from transposon Tn5
March 1, 1984

Distribution of urokinase-type plasminogen activator immunoreactivity in the mouse
January 1, 1985

Plasminogen activators, tissue degradation, and cancer
December 25, 1986

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing
April 1, 1987

Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitors
January 1, 1988

Molecular cloning of complementary DNA to mouse tissue plasminogen activator mRNA and its expression during F9 teratocarcinoma cell differentiation
February 1, 1988

Tissue plasminogen activator mRNA in murine tissues
April 1, 1989

Tissue cooperation in a proteolytic cascade activating human interstitial collagenase
July 1, 1989

Paroxysmal nocturnal hemoglobinuria
August 1990

The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes
November 1, 1991

Differential expression of urokinase-type plasminogen activator and its type-1 inhibitor during healing of mouse skin wounds
March 1, 1991

Localization of urokinase-type plasminogen activator messenger RNA in the normal mouse by in situ hybridization
November 1, 1991

In vivo paracrine interaction between urokinase and its receptor: effect on tumor cell invasion
January 1, 1991

Inhibition of urokinase-type plasminogen activator by antibodies: the effect on dissemination of a human tumor in the nude mouse
October 16, 1992

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
January 1, 1992

Urokinase-catalyzed plasminogen activation at the monocyte/macrophage cell surface: a localized and regulated proteolytic system
March 1992

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease
December 1, 1992

Fibrin and its derivatives in the normal and diseased vessel wall,Fibrin and Its Derivatives in the Normal and Diseased Vessel Wall
April 1, 1992

Identification and characterization of the murine cell surface receptor for the urokinase-type plasminogen activator
March 1, 1992

The receptor for urokinase-type plasminogen activator is deficient on peripheral blood leukocytes in patients with paroxysmal nocturnal hemoglobinuria
April 29, 1993

The pathogenesis of atherosclerosis: a perspective for the 1990s
June 1, 1993

Prevention of metastasis by inhibition of the urokinase receptor
October 1, 1993

Fibrin(ogen) is internalized and degraded by activated human monocytoid cells via Mac-1 (CD11b/CD18): a nonplasmin fibrinolytic pathway
January 1, 1993

The structural motif glycine 190-valine 202 of the fibrinogen gamma chain interacts with CD11b/CD18 integrin (alpha M beta 2, Mac-1) and promotes leukocyte adhesion
August 11, 1994

Activation of transforming growth factor-beta is inhibited in transgenic apolipoprotein(a) mice
January 1, 1994

Fibrin as a factor in atherogenesis
April 1, 1994

The receptor for urokinase-type plasminogen activator is expressed by keratinocytes at the leading edge during re-epithelialization of mouse skin wounds
March 1, 1994

Requirement for receptor-bound urokinase in plasmin-dependent cellular conversion of latent TGF-beta to TGF-beta
March 1, 1994

Physiological consequences of loss of plasminogen activator gene function in mice
June 1, 1995

Immediate early detection of urokinase receptor after partial hepatectomy and its implications for initiation of liver regeneration

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