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Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells

Published in: Proceedings of the National Academy of Sciences of the United States of America

Date of publication: June 1, 1978

Language: English

Main subject: visualization, preproinsulin

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Cites articles 22

Date

Title

Authors

April 1, 1964

ISOLATION AND BIOLOGICAL EFFECTS OF AN EPIDERMAL GROWTH-STIMULATING PROTEIN
December 1, 1966

Binding of hormone to tissue: the first step in polypeptide hormone action
December 1, 1972

Epidermal growth factor and a new derivative. Rapid isolation procedures and biological and chemical characterization
September 1973

Pituitary extracts and steroid hormones in the control of 3T3 cell growth
January 1, 1974

Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture
October 1, 1974

Diffusion controlled reaction rates in spheroidal geometry. Application to repressor--operator association and membrane bound enzymes
May 1, 1975

Insulin and epidermal growth factor. Human fibroblast receptors related to deoxyribonucleic acid synthesis and amino acid uptake
June 1, 1975

Characterization of the binding of 125-I-labeled epidermal growth factor to human fibroblasts
July 1, 1976

Lateral transport on cell membranes: mobility of concanavalin A receptors on myoblasts
October 1, 1976

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts
November 1, 1976

Dynamics of fluorescence marker concentration as a probe of mobility
April 1, 1976

Retention and degradation of 125I-insulin by perfused livers from diabetic rats
August 1, 1976

Membrane receptors for hormones and neurotransmitters
April 1, 1976

Site-site interactions among insulin receptors. Characterization of the negative cooperativity
July 1, 1976

Insulin receptors in normal and transformed fibroblasts: relationship to growth and transformation
June 1, 1976

Human epidermal growth factor and the proliferation of human fibroblasts
December 1, 1977

A mutation that impairs the ability of lipoprotein receptors to localise in coated pits on the cell surface of human fibroblasts
April 1, 1977

Cellular uptake and nuclear binding of insulin in human cultured lymphocytes: evidence for potential intracellular sites of insulin action
January 1, 1977

The natural occurrence of insulin receptors in groups on adipocyte plasma membranes as demonstrated with monomeric ferritin-insulin
May 1, 1978

Fluorescent labeling of hormone receptors in viable cells: preparation and properties of highly fluorescent derivatives of epidermal growth factor and insulin
March 1, 1978

The visualization of fluorescent proteins in living cells by video intensification microscopy (VIM).
March 1, 1978

Decreased binding of epidermal growth factor to BALB/c 3T3 mutant cells defective in glycoprotein synthesis

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