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Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitors

Published in: Journal of Cell Biology

Date of publication: April 1, 1987

Language: English

Main subject: cell surface receptor, enzyme, blood proteins, membrane protein, protein precursor, zymogen, plasminogen

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Cites articles 63

Date

Title

Authors

January 1, 1980

Plasminogen activator and the membrane of transformed cells
April 1, 1981

Released protease-nexin regulates cellular binding, internalization, and degradation of serine proteases
January 1, 1981

Human fibroblasts produce inhibitor directed against plasminogen activator when treated with glucocorticoids
March 25, 1982

Kinetics of the activation of plasminogen by human tissue plasminogen activator. Role of fibrin
May 1, 1982

Plasminogen Activator Released as Inactive Proenzyme from Murine Cells Transformed by Sarcoma Virus
December 1, 1982

Purification of zymogen to plasminogen activator from human glioblastoma cells by affinity chromatography with monoclonal antibody
March 1, 1982

Macrophage fibrinolytic activity: identification of two pathways of plasmin formation by intact cells and of a plasminogen activator inhibitor,Macrophage fibrinolytic activity: Identification of two pathways of plasmin formation by intact cells and of a plasminogen activator inhibitor
June 1, 1982

A proenzyme form of human urokinase
October 1, 1982

The primary structure of high molecular mass urokinase from human urine. The complete amino acid sequence of the A chain
November 1, 1983

Latent tissue plasminogen activator produced by human endothelial cells in culture: evidence for an enzyme-inhibitor complex
May 1, 1983

Detection of an unusually stable fibrinolytic inhibitor produced by bovine endothelial cells
August 1, 1983

Phorbol ester and mitogens stimulate human fibroblast secretions of plasmin-activatable plasminogen activator and protease nexin, an antiactivator/antiplasmin
January 1, 1983

Hormonal regulation of plasminogen activator in rat hepatoma cells
January 1, 1983

Inhibition of tissue-type plasminogen activator by conditioned medium from cultured human and porcine vascular endothelial cells
June 1, 1984

Effective and fibrin-specific clot lysis by a zymogen precursor form of urokinase (pro-urokinase). A study in vitro and in two animal species
August 1984

Identification and primary sequence of an unspliced human urokinase poly(A)+ RNA
August 1, 1984

Immunocytochemical localization of urokinase-type plasminogen activator in Lewis lung carcinoma
January 1, 1984

Monoclonal antibodies to human urokinase identify the single-chain pro-urokinase precursor
December 1, 1984

cDNA and gene nucleotide sequence of porcine plasminogen activator.
June 1, 1984

Concomitant secretion of prourokinase and of a plasminogen activator-specific inhibitor by cultured human monocytes-macrophages
March 1, 1984

Inactivation of tissue plasminogen activator in plasma. Demonstration of a complex with a new rapid inhibitor
May 1, 1984

Initial plasmin-degradation of fibrin as the basis of a positive feed-back mechanism in fibrinolysis
May 1, 1984

Purification of human fibroblast urokinase proenzyme and analysis of its regulation by proteases and protease nexin
June 1, 1984

Dexamethasone induction of an inhibitor of plasminogen activator in HTC hepatoma cells
November 1, 1984

Isolation of tissue-type plasminogen activator-inhibitor complexes from human plasma. Evidence for a rapid plasminogen activator inhibitor
December 1, 1984

Purification of an inhibitor of plasminogen activator (antiactivator) synthesized by endothelial cells
June 10, 1985

Protease nexin. Properties and a modified purification procedure
December 1, 1985

The primary plasminogen-activator inhibitors in endothelial cells, platelets, serum, and plasma are immunologically related
July 1985

Evolution of the proteases of blood coagulation and fibrinolysis by assembly from modules
January 1, 1985

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase
August 1, 1985

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes
July 1, 1985

Human urokinase gene is located on the long arm of chromosome 10.

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