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Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments

Author

Susumu Tonegawa

1939 -

John H. Rogers

1952 -

Published in: Nature

Date of publication: February 1, 1979

Language: English

Bibliographic databases:

Cites articles 40

Date

Title

Authors

December 1, 1966

The evolutionary origins of the immunoglobulins
July 1, 1966

Antibody active sites and immunoglobulin molecules
May 1, 1969

The covalent structure of an entire gammaG immunoglobulin molecule
March 1, 1969

Mapping of deletions and substitutions in heteroduplex DNA molecules of bacteriophage lambda by electron microscopy,Mapping of Deletions and Substitutions in Heteroduplex DNA Molecules of Bacteriophage Lambda by Electron Microscopy
December 1, 1973

Three-dimensional structure of the Fab' fragment of a human immunoglobulin at 2,8-A resolution
October 1, 1973

Structure at 4.5 A resolution of a phosphorylcholine-binding fab,Structure at 4.5 Å; Resolution of a Phosphorylcholine-binding Fab
November 1, 1974

Synthesis of a carboxyl-terminal (constant region) fragment of the immunoglobin light chain by a mouse myeloma cell line
November 5, 1975

Detection of specific sequences among DNA fragments separated by gel electrophoresis
January 1, 1975

Structural variants of human and murine immunoglobulins
October 1, 1976

Improved derivative of a phage lambda EK2 vector for cloning recombinant DNA
February 1, 1977

A novel arrangement of the 18S and 28S sequences in a repeating unit of drosophila melanogaster rDNA
February 1, 1977

The structural organization of ribosomal DNA in Drosophila melanogaster,The structural organization of ribosomal DNA in drosophila melanogaster
September 1, 1977

An amazing sequence arrangement at the 5' ends of adenovirus 2 messenger RNA.
February 1, 1977

R loop mapping of the 18S and 28S sequences in the long and short repeating units of drosophila melanogaster rDNA
January 1, 1977

Molecular analysis of spontaneous somatic mutants
October 1, 1977

Cloned MPC 11 myeloma cells express two kappa genes: a gene for a complete light chain and a gene for a constant region polypeptide
November 1, 1977

Ovalbumin gene is split in chicken DNA
August 1, 1977

Cloning of an immunoglobulin variable region gene from mouse embryo
August 1977

Spliced segments at the 5' terminus of adenovirus 2 late mRNA,Spliced segments at the 5′ terminus of adenovirus 2 late mRNA
December 1, 1977

Variable and constant parts of the immunoglobulin light chain gene of a mouse myeloma cell are 1250 nontranslated bases apart
December 1, 1977

The rabbit beta-globin gene contains a large large insert in the coding sequence,The rabbit β-globin gene contains a large insert in the coding sequence
November 1, 1977

The presence of ovalbumin mRNA coding sequences in multiple restriction fragments of chicken DNA
December 1, 1977

Nucleotide sequence of a mutant eukaryotic gene: the yeast tyrosine-inserting ochre suppressor SUP4-o
August 1, 1977

Packaging recombinant DNA molecules into bacteriophage particles in vitro
April 8, 1977

Screening lambdagt recombinant clones by hybridization to single plaques in situ,Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ
February 1977

A new method for sequencing DNA
September 1, 1978

A complete immunoglobulin gene is created by somatic recombination
June 1, 1978

Transcription and processing of intervening sequences in yeast tRNA genes
August 1, 1978

Structure and processing of yeast precursor tRNAs containing intervening sequences
December 1, 1978

Sequences of mouse immunoglobulin light chain genes before and after somatic changes
November 1, 1978

Comparison of cloned rabbit and mouse β-globin genes showing strong evolutionary divergence of two homologous pairs of introns
June 1, 1978

Primary structures of N-terminal extra peptide segments linked to the variable and constant regions of immunoglobulin light chain precursors: implications on the organization and controlled expression of immunoglobulin genes

Article -

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