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The presence of a defective LEU2 gene on 2 mu DNA recombinant plasmids of Saccharomyces cerevisiae is responsible for curing and high copy number.

Published in: Journal of Bacteriology

Date of publication: November 1, 1983

Main subject: Saccharomyces cerevisiae

Cites articles 25

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Eukaryotic DNA segments capable of autonomous replication in yeast
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Nucleotide sequence of yeast LEU2 shows 5'-noncoding region has sequences cognate to leucine,Nucleotide sequence of yeast LEU2 shows 5′-noncoding region has sequences cognate to leucine
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Overproduction and control of the LEU2 gene product, beta-isopropylmalate dehydrogenase, in transformed yeast strains

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