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Endothelial receptor tyrosine kinases involved in angiogenesis.

Author

Kari Alitalo

Tuija Mustonen

Published in: Journal of Cell Biology

Date of publication: May 1, 1995

Language: English

Main subject: vascular endothelium, receptor tyrosine kinase, neovascularization

Bibliographic databases:

Cites articles 46

Date

Title

Authors

April 1990

Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family
October 1, 1991

A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit
February 1, 1991

Expression of FGF receptor gene in rat development
February 1, 1992

Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation
February 1, 1992

Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors
September 30, 1992

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor
January 1, 1992

The FGF family of growth factors and oncogenes
February 1, 1992

Molecular and biological properties of the vascular endothelial growth factor family of proteins

,
October 1, 1992

FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines
April 1992

A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains
February 21, 1992

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

, ,
October 29, 1992

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
August 1, 1992

tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors
November 1, 1992

Enhanced expression of the tie receptor tyrosine kinase in endothelial cells during neovascularization
October 1, 1992

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
January 1, 1993

NYK/FLK-1: a putative receptor protein tyrosine kinase isolated from E10 embryonic neuroepithelium is expressed in endothelial cells of the developing embryo
October 15, 1993

Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system
August 1, 1993

Molecular cloning and characterization of mouse TIE and TEK receptor tyrosine kinase genes and their expression in hematopoietic stem cells
May 1, 1993

The FLT4 gene encodes a transmembrane tyrosine kinase related to the vascular endothelial growth factor receptor
March 1, 1993

Molecular cloning and characterization of a novel receptor protein tyrosine kinase from human placenta
August 15, 1993

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium
November 15, 1993

Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor
November 1, 1993

Expression of tie-2, a member of a novel family of receptor tyrosine kinases, in the endothelial cell lineage
October 1, 1993

Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth
November 1, 1993

Two human FLT4 receptor tyrosine kinase isoforms with distinct carboxy terminal tails are produced by alternative processing of primary transcripts
April 29, 1993

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
March 26, 1993

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
April 1, 1993

Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14
December 1, 1993

The related FLT4, FLT1, and KDR receptor tyrosine kinases show distinct expression patterns in human fetal endothelial cells
June 1, 1993

Distinct rat genes with related profiles of expression define a TIE receptor tyrosine kinase family
September 1, 1994

A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelial growth factor and Flt tyrosine kinase receptor family (Flt-1 and KDR/Flk-1)
December 1, 1994

Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors

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