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Death before birth: clues from gene knockouts and mutations

Author

Andrew Copp

Published in: Trends in Genetics

Date of publication: March 1, 1995

Bibliographic databases:

Cites articles 58

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FORMATION OF GENETICALLY MOSAIC MOUSE EMBRYOS, AND EARLY DEVELOPMENT OF "LETHAL (T12/T12)-NORMAL" MOSAICS
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A sex-linked defect in the cross-linking of collagen and elastin associated with the mottled locus in mice
December 1, 1976

In vitro studies of mouse embryos bearing mutations at the T locus: tw5 and t12
February 1, 1976

Congenital malformations of the central nervous system in spontaneous abortions
October 1, 1977

Frequency of chromosomal abnormalities in miscarriages and perinatal deaths
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Developmental analysis of lethal effects of homozygosity for the c25H deletion in the mouse
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Embryonic lethal mutation in mouse collagen I gene causes rupture of blood vessels and is associated with erythropoietic and mesenchymal cell death
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Maternal and embryonic factors associated with prenatal loss in mammals
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Investigation of the tissue specificity of the lethal yellow (Ay) gene in mouse embryos
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Altering the genome by homologous recombination
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Death of mouse embryos that lack a functional gene for glucose phosphate isomerase
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The embryonic development of mammalian neural tube defects

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A cell autonomous function of Brachyury in T/T embryonic stem cell chimaeras
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legless insertional mutation: morphological, molecular, and genetic characterization
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A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis
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Mice develop normally without tenascin
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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
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Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene
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Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
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Effects of an Rb mutation in the mouse
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The embryonic lethality of homozygous lethal yellow mice (Ay/Ay) is associated with the disruption of a novel RNA-binding protein
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Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation
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Morula decompaction (mdn), a preimplantation recessive lethal defect in a transgenic mouse line

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