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Recombinant fragment assay for gene targetting based on the polymerase chain reaction

Author

Oliver Smithies

1925 - 2017

Published in: Nucleic Acids Research

Date of publication: September 1, 1988

Bibliographic databases:

Cites articles 24

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Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter
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Analysis of homologous recombination in cultured mammalian cells,Analysis of Homologous Recombination in Cultured Mammalian Cells
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Homologous recombination in mouse L cells
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Homologous recombination with DNA introduced into mammalian cells
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Homologous recombination between defective neo genes in mouse 3T6 cells
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Recombination in mouse L cells between DNA introduced into cells and homologous chromosomal sequences
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Specific enzymatic amplification of DNA in vitro: the polymerase chain reaction
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High frequency targeting of genes to specific sites in the mammalian genome
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Analysis of enzymatically amplified beta-globin and HLA-DQ alpha DNA with allele-specific oligonucleotide probes
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Targeted modification of human chromosomal genes
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[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction
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Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
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Accurate modification of a chromosomal plasmid by homologous recombination in human cells
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An improved method for prenatal diagnosis of genetic diseases by analysis of amplified DNA sequences. Application to hemophilia A.
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Detection of minimal residual cells carrying the t(14;18) by DNA sequence amplification
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Targetted correction of a mutant HPRT gene in mouse embryonic stem cells
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Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction
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A simple and low cost DNA amplifier
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Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

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