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Stable and inheritable changes in genotype and phenotype of albino melanocytes induced by an RNA-DNA oligonucleotide

Published in: Nature Biotechnology

Date of publication: December 1, 1998

Language: English

Main subject: albinism

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Cites articles 20

Date

Title

Authors

October 1, 1988

Tyrosinases of murine melanocytes with mutations at the albino locus
April 1, 1990

A point mutation in the tyrosinase gene of BALB/c albino mouse causing the cysteine----serine substitution at position 85.
September 1, 1990

Identification of the albino mutation of mouse tyrosinase by analysis of an in vitro revertant
September 1, 1990

Rescue of the albino phenotype by introduction of a functional tyrosinase gene into mice
September 1, 1991

Structural aberration of the rough endoplasmic reticulum and melanosome compartmentalization in long-term cultures of melanocytes from vitiligo patients
September 1, 1994

A role for RNA synthesis in homologous pairing events
March 1, 1994

Transcription activates RecA-promoted homologous pairing of nucleosomal DNA.
March 1, 1996

Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA.DNA oligonucleotide
January 1, 1996

Mismatch repair in replication fidelity, genetic recombination, and cancer biology
March 1, 1996

Tyrosinase and related proteins in mammalian pigmentation
September 1, 1996

Correction of the mutation responsible for sickle cell anemia by an RNA-DNA oligonucleotide
July 1, 1997

Sickle cell anemia research and a recombinant DNA technique

,
November 1, 1997

Targeted gene conversion in a mammalian CD34+-enriched cell population using a chimeric RNA/DNA oligonucleotide
June 1, 1997

Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide
March 1, 1997

Recombinant DNA technique and sickle cell anemia research
April 1, 1998

Therapeutic repair of mutated nucleic acid sequences
February 1, 1998

Therapeutic gene targeting
December 1, 1998

Different frequency of gene targeting events by the RNA-DNA oligonucleotide among epithelial cells
March 1, 1998

In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides
March 1, 1998

The site-specific correction of genetic defects

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