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Shutdown of class switch recombination by deletion of a switch region control element.

Author

Steffen Jung

1961 -

Klaus Rajewsky

1936 -

Andreas Radbruch

1952 -

Published in: Science

Date of publication: February 1, 1993

Language: English

Bibliographic databases:

Cites articles 19

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T cell-derived B cell differentiation factor(s). Effect on the isotype switch of murine B cells
March 1, 1982

Organization of the constant-region gene family of the mouse immunoglobulin heavy chain
June 1, 1986

Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts

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Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
July 1, 1988

Interleukin 4 instructs uncommitted B lymphocytes to switch to IgG1 and IgE.
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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
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Mitogen plus interleukin 4 induction of C epsilon transcripts in B lymphoid cells
April 1, 1989

Synthesis of germ-line gamma 1 immunoglobulin heavy-chain transcripts in resting B cells: induction by interleukin 4 and inhibition by interferon gamma

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January 1, 1989

An interleukin 4-induced DNase I hypersensitive site indicates opening of the gamma 1 switch region prior to switch recombination
March 1, 1989

An initiation site for meiotic gene conversion in the yeast Saccharomyces cerevisiae
October 1, 1990

Protective methylation of immunoglobulin and T cell receptor (TcR) gene loci prior to induction of class switch and TcR recombination
January 1, 1990

Immunoglobulin class switching: molecular and cellular analysis
January 1, 1990

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells,Structure of Germline Immunoglobulin Heavy-Chainγ1 Transcripts in Interleukin 4 Treated Mouse Spleen Cells
April 1, 1991

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene
March 15, 1991

Recombinase-mediated gene activation and site-specific integration in mammalian cells
January 1, 1991

A poly(dA.dT) tract is a component of the recombination initiation site at the ARG4 locus in Saccharomyces cerevisiae
November 1, 1991

Generation and analysis of interleukin-4 deficient mice
May 1, 1992

Transcriptional regulatory elements stimulate recombination in extrachromosomal substrates carrying immunoglobulin switch-region sequences
March 19, 2017

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

Article -

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