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Inhibition of the Lysosomal Pathway of Protein Degradation in Isolated Rat Hepatocytes by Ammonia, Methylamine, Chloroquine and Leupeptin

Author

Per Ottar Seglen

1943 -

published in: FEBS Journal

date of publication: 1979-04-01

language: inglese

main subject: clorochina, biochimica

Bibliographic databases:

Cites articles 46

Date

Title

Authors

1967-11

Participation of lysosomes in cellular autophagy induced in rat liver by glucagon
1973-12-01

The diurnal response of muscle and liver protein synthesis in vivo in meal-fed rats
1973-12-01

Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion
1973-11-01

Effects of anaerobiosis, glucose, insulin and glucagon on glycogen metabolism in isolated parenchymal rat liver cells.
1974-11-01

Protein degradation in cultured cells. II. The uptake of chloroquine by rat fibroblasts and the inhibition of cellular protein degradation and cathepsin B1.
1974-07-01

Localization of products of endogenous proteolysis in lysosomes of perfused rat liver.
1975-09-01

Protein degradation in isolated rat hepatocytes is inhibited by ammonia
1975-11-01

Requirement for protein synthesis in the regulation of protein breakdown in cultured hepatoma cells
1975-11-01

Further evidence for a proton pump in mouse kidney phagolysosomes: Effect of nigericin and 2,4-dinitrophenol on the stimulation of intralysosomal proteolysis by ATP
1976-06-01

Selective control of the degradation of normal and aberrant proteins in Reuber H35 hepatoma cells
1976-01-01

Effects of cycloheximide on protein degradation and gluconeogenesis in the perfused rat liver
1976-10-01

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts
1976-01-01

Intracellular protein degradation in mammalian and bacterial cells: Part 2
1976-08-01

Role of protein degradation in the growth of livers after a nutritional shift
1976-07-01

Ammonia inhibition of protein degradation in isolated rat hepatocytes. Quantitative ultrastructural alterations in the lysosomal system
1976

Preparation of isolated rat liver cells,Chapter 4 Preparation of Isolated Rat Liver Cells
1976-09-01

Incorporation of radioactive amino acids into protein in isolated rat hepatocytes
1976-10-01

Relationship between medium pH and that of the lysosomal matrix as studied by two independent methods
1976-03-01

Delayed degeneration of dystrophic and normal muscle cell cultures treated with pepstatin, leupeptin, and antipain
1976-10-01

Synthesis and degradation of proteins in cultured, androgen-responsive tumour cells
1977-11-01

Effect of microtubular or translational inhibitors on general cell protein degradation. Evidence for a dual catabolic pathway
1977-08-01

Uptake and degradation of 125I-labelled asialo-fetuin by isolated rat hepatocytes
1977-05-01

Inhibition of protein degradation in isolated rat hepatocytes
1977-11-01

The permeability properties of the lysosomal membrane
1977-05-01

Effect of a nutritional shift on the degradation of abnormal proteins in the mouse liver. Decreased degradation during rapid liver growth
1977

A neutral proteinase from rat intestinal muscle [proceedings]
1977-01

A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes
1977-11-01

Induction of autophagy by amino-acid deprivation in perfused rat liver
1977-01-01

Protein-catabolic stage of isolated rat hepatocytes
1977-06-01

Inhibitor of protein degradation formed during incubation of isolated rat hepatocytes in a cell culture medium. Its identification as ammonia
1977-04-01

Cathepsin L. A New Proteinase from Rat-Liver Lysosomes
1977-06-01

Effect of medium composition on protein degradation and DNA synthesis in rat embryo fibroblasts

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