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SMADs: mediators and regulators of TGF-beta signaling

Published in: Current Opinion in Genetics & Development

Date of publication: February 1, 1998

Bibliographic databases:

Cites articles 40

Date

Title

Authors

August 1, 1992

Effect of protein and steroidal osteotropic agents on differentiation and epidermal growth factor-mediated growth of the CFK1 osseous cell line
January 1, 1993

FGF-4 and BMP-2 have opposite effects on limb growth
December 1, 1995

Identification of a potential regulator of early transcriptional responses to mesoderm inducers in the frog embryo
October 12, 1995

A WD-domain protein that is associated with and phosphorylated by the type II TGF-beta receptor
July 1, 1996

Bone morphogenetic proteins: multifunctional regulators of vertebrate development
June 1, 1996

TGFbeta signaling: receptors, transducers, and Mad proteins
August 1, 1996

Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth
June 1, 1996

A human Mad protein acting as a BMP-regulated transcriptional activator
July 26, 1996

Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1
May 17, 1996

MADR1, a MAD-related protein that functions in BMP2 signaling pathways
May 1, 1996

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily
January 23, 1996

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components
September 12, 1996

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response
December 27, 1996

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling
August 23, 1996

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

, ,
August 1, 1996

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway
October 24, 1996

A transcriptional partner for MAD proteins in TGF-beta signalling
January 1, 1996

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1.
October 1, 1996

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways

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August 1, 1996

The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.
July 1996

Mad-related genes in the human

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June 15, 1997

Cloning and characterization of a novel member of the human Mad gene family (MADH6)
April 1, 1997

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase
January 1, 1997

Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway
July 1, 1997

Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

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December 1, 1997

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes
May 1, 1997

TGF-beta signalling through the Smad pathway
May 1997

Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4
September 4, 1997

Smad4 and FAST-1 in the assembly of activin-responsive factor
July 3, 1997

A structural basis for mutational inactivation of the tumour suppressor Smad4

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July 1, 1997

Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
July 1, 1997

Mechanism of TGFbeta receptor inhibition by FKBP12

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