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The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility

published in: The EMBO Journal

date of publication: 1998-01-01

language: inglese

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Cites articles 43

Date

Title

Authors

1978-08-01

Differential expression of Rous Sarcoma virus-specific transformation parameters in enucleated cells
1979-01-01

Immunofluorescence on avian sarcoma virus-transformed cells: Localization of the src gene product
1980-07-01

The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane
1982-09-01

Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide
1984-03-01

Size-variant pp60src proteins of recovered avian sarcoma viruses interact with adhesion plaques as peripheral membrane proteins: effects on cell transformation,Size-Variant pp60src Proteins of Recovered Avian Sarcoma Viruses Interact with Adhesion Plaques as Peripheral Membrane Proteins: Effects on Cell Transformation
1984-09-01

A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation
1985-07-01

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation
1986-07-01

The use of Rous sarcoma virus transformation mutants with differing tyrosine kinase activities to study the relationships between vinculin phosphorylation, pp60v-src location and adhesion plaque integrity
1988-06-01

A single point mutation has pleiotropic effects on pp60v-src function
1988-11

Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton,Focal Adhesions: Transmembrane Junctions Between the Extracellular Matrix and the Cytoskeleton
1989-06-01

Structural differences between repressed and derepressed forms of p60c-src
1990-05-01

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases
1990-12-01

Immunolocalization of the cellular src protein in interphase and mitotic NIH c-src overexpresser cells
1991-10-01

Transmembrane molecular assemblies in cell-extracellular matrix interactions
1992-08-07

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

,
1992-08-07

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
1992-06-01

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions
1992-09-01

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin
1992-11

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly
1992-08-20

Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation
1992-07-01

Association of p60c-src with endosomal membranes in mammalian fibroblasts

,
1992-11-01

Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase
1993-07-01

SH2 and SH3 domains
1993-01-01

Signalling through SH2 and SH3 domains
1993-07-01

Mitogenesis of quiescent chick fibroblasts by v-Src: dependence on events at the membrane leading to early changes in AP-1
1993-11-01

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions
1994-05-01

Excess early signaling activity inhibits cellular chemotaxis toward PDGF-BB
1994-11-01

Separation of v-Src-induced mitogenesis and morphological transformation by inhibition of AP-1
1994-08-01

Protein tyrosine kinases, with emphasis on the Src family
1994-10-01

Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527.

,
1994-03-01

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src
1995-06-01

v-Src-induced degradation of focal adhesion kinase during morphological transformation of chicken embryo fibroblasts

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