Siân Jones - Author - Inventaire

Siân Jones

occupation: researcher

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Articles 38

Date

Title

Authors

2017-05-01

Cancer-Associated Mutations in Endometriosis without Cancer.

Bert Vogelstein, Siân Jones, Ayşe Ayhan, Luis Alberto Diaz Jr, Kenneth W Kinzler, Blake Gilks, Laura D Wood, Nickolas Papadopoulos, K Wyatt McMahon, Cristian Tomasetti, Austin Mattox, Maria Popoli
2016-09-16

CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network

Siân Jones, Ruchira Ranaweera, Elana J. Fertig
2016-04-19

Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors

Siân Jones, Victor Velculescu
2015-07-07

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

Siân Jones, Victor Velculescu, Luis Alberto Diaz Jr, Ralph H. Hruban, Anirban Maitra, David S Klimstra, James R Eshleman, Mark Sausen, Jillian Phallen, Vilmos Adleff, Rebecca J Leary, Valsamo Anagnostou, Sonya Parpart-Li, Carolyn Hruban, Daniel D Von Hoff, Jeffrey Drebin
2015-03-01

Familial and sporadic pancreatic cancer share the same molecular pathogenesis

Bert Vogelstein, Siân Jones, Nicholas J Roberts, Kenneth W Kinzler, Ralph H. Hruban, James R Eshleman, Alison P Klein, Alexis L Norris, Nickolas Papadopoulos, Sarah Wheelan
2015-04-01

Personalized genomic analyses for cancer mutation discovery and interpretation

Samuel V Angiuoli, Siân Jones, Victor Velculescu, Luis Alberto Diaz Jr, Monica Nesselbush, Mark Sausen, Valsamo Anagnostou, Sonya Parpart-Li, Lisa Kann, Manish R Shukla, Karli Lytle, Eniko Papp, Theresa Zhang
2014-06-01

Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas

Siân Jones, Zachary J Reitman, Henry Seth Friedman, Darell D. Bigner, Allan Friedman, Roger E McLendon, Patrick J Killela, Huishan Zhu
2014-03-14

Integrated next-generation sequencing and avatar mouse models for personalized cancer treatment

Samuel V Angiuoli, Alfonso Valencia, Siân Jones, Pedro P López-Casas, Antonio Calles, Victor Velculescu, Luis Alberto Diaz Jr, Manuel Hidalgo, David Sidransky, Elena Garralda, Fátima Al-Shahrour, Lisa Kann
2014-09-19

Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes

Samuel V Angiuoli, Siân Jones, Victor Velculescu, Luis Alberto Diaz Jr, Laura D Wood, Mark Sausen, Lisa Kann, Christine L McCord, Manish R Shukla
2014-01-16

Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma

Siân Jones
2013-01

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma

Bert Vogelstein, Kenneth W Kinzler, Victor Velculescu, Siân Jones, Luis Alberto Diaz Jr, Nickolas Papadopoulos, Rebecca J Leary, Mark Sausen, Amanda Blackford, Michael D Hogarty
2013-05-31

Therapeutic potential of the poly(ADP-ribose) polymerase inhibitor rucaparib for the treatment of sporadic human ovarian cancer

Charles Ginther, Judy Dering, Boris Winterhoff, Meenal Chalukya, Kanthinh Manivong, Siân Jones, Victor Velculescu
2012-09-18

Clinical significance of the genetic landscape of pancreatic cancer and implications for identification of potential long-term survivors

Siân Jones, Victor Velculescu, Christine A Iacobuzio-Donahue, Ralph H. Hruban, Christopher L Wolfgang, Daniel A Laheru, Alison P Klein, Yoshiki Naito, Shinichi Yachida, Jacqueline A Brosnan-Cashman
2011-01

Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer

Ralph H. Hruban, Siân Jones, Ignacio Garrido-Laguna, Anirban Maitra, James R Eshleman, Alison P Klein, Daniel A Laheru, Ross C Donehower, Ana De Jesus-Acosta
2011-03-15

Expression of p16 and retinoblastoma determines response to CDK4/6 inhibition in ovarian cancer

Victor Velculescu, Charles Ginther, Judy Dering, Boris Winterhoff, Meenal Chalukya, Kanthinh Manivong, Siân Jones, Lynn C. Hartmann, Kimberly R Kalli, Gottfried E Konecny, William A Cliby, Dennis Slamon
2011-01-28

The genetic landscape of the childhood cancer medulloblastoma

Bert Vogelstein, Siân Jones, Simina M. Boca, Victor Velculescu, Tom Curran, Henry Seth Friedman, Darell D. Bigner, Kenneth W Kinzler, Roger E McLendon, George Jallo, Peter C. Burger, Chetan Bettegowda, Paul A Northcott, Adam C Resnick, Gary L Gallia, Mitchel S Berger, Suely Kazue Nagahashi Marie, Sueli Mieko Oba Shinjo, Stephen T Keir, Xiaosong Zhang, Rebecca J Leary, Jimmy Cheng-Ho Lin, Rachel Karchin, Zev A Binder, Daniela S Gerhard
2011-11-23

Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

Marjanka K Schmidt, Bert Vogelstein, Siân Jones, Victor Velculescu, Darell D. Bigner, Kenneth W Kinzler, Christine A Iacobuzio-Donahue, Michael Goggins, Ralph H. Hruban, Anirban Maitra, James R Eshleman, Xiaosong Zhang, Nickolas Papadopoulos, Sanford D Markowitz, Sami N Malek
2011-09-27

Radiofrequency ablation for treatment of symptomatic uterine fibroids

Siân Jones
2011-12-20

Low-grade serous carcinomas of the ovary contain very few point mutations

Bert Vogelstein, Siân Jones, Victor Velculescu, Kenneth W Kinzler, Nickolas Papadopoulos, Kentaro Nakayama
2010-10-28

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Bert Vogelstein, Kenneth W Kinzler, Ralph H. Hruban, Victor Velculescu, Siân Jones, Ivana Bozic, Christine A Iacobuzio-Donahue, Martin A. Nowak, James R Eshleman, Tibor Antal, Shinichi Yachida, Rebecca J Leary, Mihoko Kamiyama
2010-10-08

Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma

Bert Vogelstein, Siân Jones, Victor Velculescu, Luis Alberto Diaz Jr, Kenneth W Kinzler, Richard B S Roden, Nickolas Papadopoulos, Kentaro Nakayama
2009-02-19

IDH1 and IDH2 mutations in gliomas

Bert Vogelstein, Kenneth W Kinzler, Victor Velculescu, Siân Jones, Henry Seth Friedman, Darell D. Bigner, Allan Friedman, David A Reardon, Roger E McLendon, Ines Batinic-Haberle, James H. Herndon, Genglin Jin
2009-04-15

Genetic mutations associated with cigarette smoking in pancreatic cancer

Bert Vogelstein, Kenneth W Kinzler, Ralph H. Hruban, Victor Velculescu, Siân Jones, Kelly Olino, Christine A Iacobuzio-Donahue, Michael Goggins, Elizabeth Jaffee, Christopher L Wolfgang, Richard D Schulick, Anirban Maitra, James R Eshleman, Alison P Klein, Amanda Blackford, Xiaosong Zhang, Jimmy Cheng-Ho Lin, Rebecca J Leary, Jordan M Winter
2009-04-10

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

Bert Vogelstein, Kenneth W Kinzler, Ralph H. Hruban, Victor Velculescu, Siân Jones, Christine A Iacobuzio-Donahue, Michael Goggins, Elizabeth Jaffee, Anirban Maitra, James R Eshleman, Alison P Klein, Kieran Brune, Xiaosong Zhang, Jimmy Cheng-Ho Lin, Mihoko Kamiyama, Michael Borges, Emily Palmisano
2009-07-15

SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer

Bert Vogelstein, Kenneth W Kinzler, Ralph H. Hruban, Victor Velculescu, Siân Jones, Kelly Olino, Christine A Iacobuzio-Donahue, Michael Goggins, Elizabeth Jaffee, Christopher L Wolfgang, John L Cameron, Richard D Schulick, Anirban Maitra, James R Eshleman, Alison P Klein, Daniel A Laheru, Amanda Blackford, Xiaosong Zhang, Jimmy Cheng-Ho Lin, Rebecca J Leary, Jordan M Winter
2009-04-06

Frequent activating mutations of PIK3CA in ovarian clear cell carcinoma

Siân Jones, Kuan-Ting Kuo, Ayşe Ayhan, Victor Velculescu
2009-10-01

The APC Variant p.Glu1317Gln predisposes to colorectal adenomas by a novel mechanism of relaxing the target for tumorigenic somatic APC mutations

Siân Jones, Anthony R Dallosso
2008-09-26

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

Bert Vogelstein, Kenneth W Kinzler, Ralph H. Hruban, Victor Velculescu, Seung-Mo Hong, Manuel Hidalgo, Siân Jones, Anirban Maitra, Michael Goggins, Christine A Iacobuzio-Donahue, Elizabeth Jaffee, James R Eshleman, Steven Leach, Alison P Klein, Xiaosong Zhang, Jimmy Cheng-Ho Lin, Rebecca J Leary, Hirohiko Kamiyama, Ming-Tseh Lin, Eric S Calhoun, Mihoko Kamiyama, Rachel Karchin, Nickolas Papadopoulos, Philipp Angenendt, Parminder Mankoo
2008-09-26

An integrated genomic analysis of human glioblastoma multiforme

Bert Vogelstein, Kenneth W Kinzler, Victor Velculescu, Alessandro Olivi, Siân Jones, Luis Alberto Diaz Jr, Darell D. Bigner, Roger E McLendon, Stephen T Keir, Sueli Mieko Oba Shinjo, Philipp Angenendt, Parminder Mankoo, Xiaosong Zhang, Rebecca J Leary, Jimmy Cheng-Ho Lin, Gary L Gallia, Robert L. Strausberg, Suely Kazue Nagahashi Marie, Rachel Karchin
2008-10-21

Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers

Bert Vogelstein, Kenneth W Kinzler, Victor Velculescu, Siân Jones, Simina M. Boca, Laura D Wood, Jimmy Cheng-Ho Lin, Sanford D Markowitz, Rebecca J Leary, Levy Kopelovich, James Agnew, Jordan M Cummins, Tobias Sjöblom, Len A. Pennacchio
2008-04-01

Genome-wide linkage scan for colorectal cancer susceptibility genes supports linkage to chromosome 3q.

Bert Vogelstein, Jana Vandrovcova, Siân Jones, Victor Velculescu, Annika Lindblom
2008-03-12

Comparative lesion sequencing provides insights into tumor evolution

Bert Vogelstein, Siân Jones, Niko Beerenwinkel, Victor Velculescu, Kenneth W Kinzler, Martin A. Nowak, Sanford D Markowitz, Tibor Antal, Arne Traulsen

Human - wd:Q42696646

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