Little Science, Big Science is a book of collected lectures given by Derek J. De Solla Price, first published in 1963. The book presents the 1962 Brookhaven National Laboratory Pegram Lectures, a series of lectures dedicated to discussing science and its place in society. Price's goal in the lectures is to outline what it may look like for science to be analysed scientifically, by applying methods of measuring, hypothesizing, and deriving to science itself. With this goal in mind, he sets out to define quasi-mathematically how the shape and size of science has shifted from "small science" to "big science" in a historical and sociological way. Price presents a quantification of science as a measurable entity via an analogy to thermodynamics, conceptualizing science like a gas with individual molecules possessing individual velocities and interactions, a total volume, and general properties or laws. Source: Wikipedia (en)