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Transforming protein of simian sarcoma virus stimulates autocrine growth of SSV-transformed cells through PDGF cell-surface receptors

Published in: Cell

Date of publication: November 1, 1984

Language: English

Main subject: dysplasia

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Cites articles 34

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Autocrine secretion and malignant transformation of cells.
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Similarities between fibroblast-derived growth factor and platelet-derived growth factor
June 1, 1981

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Three distinct genes in human DNA related to the transforming genes of mammalian sarcoma retroviruses

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Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells.

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Platelet-derived growth factor stimulates tyrosine-specific protein kinase activity in Swiss mouse 3T3 cell membranes
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Platelet-derived growth factor binds specifically to receptors on vascular smooth muscle cells and the binding becomes nondissociable
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Synthesis of a PDGF-like growth factor in human glioma and sarcoma cells suggests the expression of the cellular homologue to the transforming protein of simian sarcoma virus

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Expression of a Platelet-Derived Growth Factor-Like Protein in Simian Sarcoma Virus Transformed Cells
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Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor
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Human platelet-derived growth factor: radioimmunoassay and discovery of a specific plasma-binding protein
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5′ Viral and Human Cellular Sequences Corresponding to the Transforming Gene of Simian Sarcoma Virus

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Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor
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Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus
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Human-Proto-Oncogene Nucleotide Sequences Corresponding to the Transforming Region of Simian Sarcoma Virus

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