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Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase

Published in: Science

Date of publication: November 1, 1994

Language: English

Main subject: Parkinson's disease

Bibliographic databases:

Cites articles 50

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Treatment of parkinsonism with levodopa,Treatment of Parkinsonism With Levodopa
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Restoration of dopaminergic function by grafting of fetal rat substantia nigra to the caudate nucleus: long-term behavioral, biochemical, and histochemical studies

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Latency competence of thirteen HSV-1 temperature-sensitive mutants,Latency Competence of Thirteen HSV-1 Temperature-sensitive Mutants
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Demonstration of a pallidostriatal pathway by retrograde transport of HRP-labeled lectin
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The immunocytochemical detection ofHerpes simplex virus in cervical smears—a valuable technique for routine use
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The nucleotide sequence of a rat 18 S ribosomal ribonucleic acid gene and a proposal for the secondary structure of 18 S ribosomal ribonucleic acid
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Differential activation of hybrid genes containing herpes simplex virus immediate-early or delayed-early promoters after superinfection of stable DNA-transfected cell lines
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Complete DNA sequence of the short repeat region in the genome of herpes simplex virus type 1.
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Fetal neuronal grafts in monkeys given methylphenyltetrahydropyridine
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Biochemical and behavioral correction of MPTP Parkinson-like syndrome by fetal cell transplantation
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Isolation and characterization of the human tyrosine hydroxylase gene: identification of 5' alternative splice sites responsible for multiple mRNAs
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Tyrosine hydroxylase-immunoreactive intrinsic neurons in the rat cerebral cortex
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A single human gene encoding multiple tyrosine hydroxylases with different predicted functional characteristics
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RNA complementary to a herpesvirus alpha gene mRNA is prominent in latently infected neurons
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A defective HSV-1 vector expresses Escherichia coli beta-galactosidase in cultured peripheral neurons
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A latent, nonpathogenic HSV-1-derived vector stably expresses beta-galactosidase in mouse neurons
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Infection of cultured central nervous system neurons with a defective herpes simplex virus 1 vector results in stable expression of Escherichia coli beta-galactosidase
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Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease

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