Harry T. Orr

1949 -

নাগরিকত্ব: মার্কিন যুক্তরাষ্ট্র

কথিত, লিখিত অথবা স্বাক্ষরিত ভাষা: ইংরেজি ভাষা

শিক্ষালাভ করেছেন: ওয়াশিংটন ইউনিভার্সিটি ইন সেন্ট লুইস

পেশা: গবেষক

প্রাপ্ত পুরস্কার: Kavli Prize in Neuroscience

Series

এখানে কিছুই নেই

নতুন সিরিজ তৈরি করুন

Works

এখানে কিছুই নেই

নতুন কাজ তৈরি করুন

নিবন্ধসমূহ 112

তারিখ

শিরোনাম

লেখকগণ

2021-03-11

Dual targeting of brain region-specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1

Maxime Rousseaux, Harry T. Orr, Huda Zoghbi
2017-03-13

Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans

Qiumin Tan, Maxime Rousseaux, Szu-Ying Yeh, Maria H Chahrour, Richard H. Finnell, Maria E Zurita-Jimenez, Kwame Anyane-Yeboa, Julien Thevenon, Harry T. Orr, Christian P Schaaf, Huda Zoghbi
2017-08-17

Polyglutamine spinocerebellar ataxias - from genes to potential treatments.

Harry T. Orr
2016-01-04

Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns

Deepali Malhotra, Thamotharampillai Dileepan, Brian T. Fife, Harry T. Orr, Marc K. Jenkins
2016-09-30

Visualizing and mapping the cerebellum with serial optical coherence scanner

Chao J Liu, Harry T. Orr, Taner Akkin
2016-03-02

Cerebellar Transcriptome Profiles of ATXN1 Transgenic Mice Reveal SCA1 Disease Progression and Protection Pathways

Harry T. Orr, Huda Zoghbi
2016-08-01

Diminishing return for mechanistic therapeutics with neurodegenerative disease duration?: There may be a point in the course of a neurodegenerative condition where therapeutics targeting disease-causing mechanisms are futile

Harry T. Orr
2016-12-01

Extensive cryptic splicing upon loss of RBM17 and TDP43 in neurodegeneration models.

Harry T. Orr, Huda Zoghbi, Qiumin Tan, Zhandong Liu, Antonia De Maio
2015-03-12

Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels

Ravi K. Singh, Vincenzo Alessandro Gennarino, Harry T. Orr, Huda Zoghbi, Antonia De Maio
2015-01-14

Early activation of microglia and astrocytes in mouse models of spinocerebellar ataxia type 1

Harry T. Orr
2015-05-19

A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1

Maxime Rousseaux, Harry T. Orr, Huda Zoghbi, Rakez Kayed, Marcos J Guerrero-Muñoz, Cristian A. Lasagna Reeves
2015-12-17

Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes

Maxime Rousseaux, Harry T. Orr, Huda Zoghbi, Rakez Kayed, Cristian A. Lasagna Reeves
2015-08-01

Neuronal Atrophy Early in Degenerative Ataxia Is a Compensatory Mechanism to Regulate Membrane Excitability

James M Dell'Orco, Yuan-Shih Hu, Harry T. Orr
2014-11-29

Assessing recovery from neurodegeneration in spinocerebellar ataxia 1: Comparison of in vivo magnetic resonance spectroscopy with motor testing, gene expression and histology

Gulin Oz, Lynn E. Eberly, Harry T. Orr
2014-09-23

Prioritized research recommendations from the National Institute of Neurological Disorders and Stroke Parkinson's Disease 2014 conference.

Randall J. Bateman, Katrina Gwinn, Story C. Landis, অ্যানা টেলর, Kip Ludwig, Harry T. Orr, Andrew Siderowf, Thomas J Montine
2013-05-29

RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1

Qiumin Tan, Chad Shaw, Simon J. Arthur, Harry T. Orr, Huda Zoghbi, Jean Woo
2013-03-01

Purkinje cell ataxin-1 modulates climbing fiber synaptic input in developing and adult mouse cerebellum

Harry T. Orr, Huda Zoghbi
2013-05-01

Polyglutamine disease toxicity is regulated by Nemo-like kinase in spinocerebellar ataxia type 1.

Hyoungseok Ju, Harry T. Orr, Huda Zoghbi
2013-03-01

14-3-3 binding to Ataxin-1 (ATXN1) regulates its dephosphorylation at Ser-776 and transport to the nucleus

Shaojuan Lai, Huda Zoghbi, Harry T. Orr
2012-06

Polyglutamine neurodegeneration: expanded glutamines enhance native functions

Harry T. Orr
2011-10-01

FTD and ALS: genetic ties that bind

Harry T. Orr
2011-05-01

Are polyglutamine diseases expanding?

Harry T. Orr
2011-01-18

Regional rescue of spinocerebellar ataxia type 1 phenotypes by 14-3-3epsilon haploinsufficiency in mice underscores complex pathogenicity in neurodegeneration

ক্রিস্টোফার এস ওয়ার্ড, Harry T. Orr, Huda Zoghbi
2011-03-22

Partial loss of Tip60 slows mid-stage neurodegeneration in a spinocerebellar ataxia type 1 (SCA1) mouse model

Harry T. Orr, Huda Zoghbi, J. Michael Andresen
2011-09-01

Abnormalities in the climbing fiber-Purkinje cell circuitry contribute to neuronal dysfunction in ATXN1[82Q] mice

Harry T. Orr
2011-08-11

14-3-3 Binding to ataxin-1(ATXN1) regulates its dephosphorylation at Ser-776 and transport to the nucleus

Shaojuan Lai, Harry T. Orr, Huda Zoghbi
2011-09-22

In vivo monitoring of recovery from neurodegeneration in conditional transgenic SCA1 mice

Gulin Oz, Lynn E. Eberly, Harry T. Orr
2011-11-01

Exercise and genetic rescue of SCA1 via the transcriptional repressor Capicua

Chad Shaw, Harry T. Orr, Huda Zoghbi
2011-08-01

Aminopyridines correct early dysfunction and delay neurodegeneration in a mouse model of spinocerebellar ataxia type 1

Harry T. Orr, Serge N. Schiffmann, Alban de Kerchove d'Exaerde
2010-09-01

SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776.

Harry T. Orr, Huda Zoghbi, J. Michael Andresen
2010-03-01

Noninvasive detection of presymptomatic and progressive neurodegeneration in a mouse model of spinocerebellar ataxia type 1

Gulin Oz, Lynn E. Eberly, Harry T. Orr
2010-05-01

Nuclear ataxias

Harry T. Orr

মানুষ - wd:Q47823272

জায়ে আপনাকে স্বাগত

the library of your friends and communities

আরো জানুন