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Ultra-low doses of naltrexone or etorphine increase morphine's antinociceptive potency and attenuate tolerance/dependence in mice

Published in: Brain Research

Date of publication: May 1, 1997

Language: English

Main subject: naltrexone, Low-dose naltrexone

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Cites articles 46

Date

Title

Authors

June 1, 1967

Novel analgesics and molecular rearrangements in the morphine-thebaine group. 3. Alcohols of the 6,14-endo-ethenotetrahydrooripavine series and derived analogs of N-allylnormorphine and -norcodeine,Novel analgesics and molecular rearrangements in the morphine-thebaine group. III. Alcohols of the 6,14-endo-ethenotetrahydrooripavine series and derived analogs of N-allylnormorphine and -norcodeine
May 1967

Actions of etorphine hydrochloride, (M99): a potent morphine-like agent
April 1, 1974

Naloxone-precipitated jumping activity in mice following the acute administration of morphine
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Responsivity to naloxone during morphine dependence
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Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine
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Naloxone dose dependently produces analgesia and hyperalgesia in postoperative pain
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Enkephalin inhibits release of substance P from sensory neurons in culture and decreases action potential duration
December 1, 1981

Dose-dependent analgesic and hyperalgesic effects of systemic naloxone in arthritic rats
September 1, 1985

A pharmacological overview of opioid mechanisms mediating analgesia and hyperalgesia
June 1, 1985

Postoperative pain relief with naloxone. Severe respiratory depression and pain after high dose buprenorphine
April 1, 1986

Analgesia produced by low doses of the opiate antagonist naloxone in arthritic rats is reduced in morphine-tolerant animals
September 1, 1987

Opioid delta-receptor involvement in supraspinal and spinal antinociception in mice
July 1, 1988

Opioids excite rather than inhibit sensory neurons after chronic opioid exposure of spinal cord-ganglion cultures
March 1, 1988

Naltrexone. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the management of opioid dependence
January 1, 1988

"Paradoxical" analgesia induced by naloxone and naltrexone
November 1, 1988

Potentiation of pentazocine analgesia by low-dose naloxone
October 1, 1989

Naloxone analgesia: an update
July 1, 1989

Dual opioid modulation of the action potential duration of mouse dorsal root ganglion neurons in culture
February 1, 1990

Opioids can evoke direct receptor-mediated excitatory effects on sensory neurons
January 1, 1990

Naloxone-induced analgesia and morphine supersensitivity effects are contingent upon prior exposure to analgesic testing
August 1, 1990

Cholera toxin-A subunit blocks opioid excitatory effects on sensory neuron action potentials indicating mediation by Gs-linked opioid receptors
October 1, 1990

Cholera toxin-B subunit blocks excitatory effects of opioids on sensory neuron action potentials indicating that GM1 ganglioside may regulate Gs-linked opioid receptor functions
November 1, 1991

Identification of a Gs activator region of the beta 2-adrenergic receptor that is autoregulated via protein kinase A-dependent phosphorylation,Identification of a Gs activator region of the β2-adrenergic receptor that is autoregulated via protein kinase A-dependent phosphorylation
September 1, 1991

Brief treatment of sensory ganglion neurons with GM1 ganglioside enhances the efficacy of opioid excitatory effects on the action potential
March 1, 1992

After chronic opioid exposure sensory neurons become supersensitive to the excitatory effects of opioid agonists and antagonists as occurs after acute elevation of GM1 ganglioside
November 1, 1992

Chronic selective activation of excitatory opioid receptor functions in sensory neurons results in opioid 'dependence' without tolerance
November 1, 1993

Inhibition of the antianalgesic action of dynorphin A in mice by cholera toxin
April 1, 1993

Direct coupling of opioid receptors to both stimulatory and inhibitory guanine nucleotide-binding proteins in F-11 neuroblastoma-sensory neuron hybrid cells
December 1, 1993

Inhibiting a spinal dynorphin A component enhances intrathecal morphine antinociception in mice
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Antinociceptive effect of dihydroetorphine and its tolerance/dependence liability in mice
February 1, 1994

Antagonists at excitatory opioid receptors on sensory neurons in culture increase potency and specificity of opiate analgesics and attenuate development of tolerance/dependence
September 1, 1994

Nerve growth factor rapidly prolongs the action potential of mature sensory ganglion neurons in culture, and this effect requires activation of Gs-coupled excitatory kappa-opioid receptors on these cells

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