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Expressing a human proinsulin cDNA in a mouse ACTH-secreting cell. Intracellular storage, proteolytic processing, and secretion on stimulation

Published in: Cell

Date of publication: December 1, 1983

Language: English

Main subject: cell line, proteolysis

Bibliographic databases:

Cites articles 22

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Title

Authors

July 1, 1968

Porcine proinsulin: characterization and amino acid sequence
August 15, 1970

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
April 1973

A new technique for the assay of infectivity of human adenovirus 5 DNA
March 1, 1974

A recognition marker required for uptake of a lysosomal enzyme by cultured fibroblasts
June 1, 1980

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling
November 1, 1980

Secretion of acetylcholinesterase: relation to acetylcholine receptor metabolism
December 1, 1980

Intracellular transport of secretory and membrane proteins in hepatoma cells infected by vesicular stomatitis virus
March 1, 1981

Biochemical studies of the human thymocyte cell-surface antigens T6, T9 and T10.
January 1, 1982

Post-translational proteolysis in polypeptide hormone biosynthesis
December 1, 1982

Construction of influenza haemagglutinin genes that code for intracellular and secreted forms of the protein
January 1, 1982

Two distinct intracellular pathways transport secretory and membrane glycoproteins to the surface of pituitary tumor cells
October 1, 1982

Use of recombinant DNA technology to program eukaryotic cells to synthesize rat proinsulin: a rapid expression assay for cloned genes
June 1, 1982

Differential regulation of metallothionein-thymidine kinase fusion genes in transgenic mice and their offspring
June 1, 1982

Regulated expression of human growth hormone genes in mouse cells
October 1, 1982

Expression from cloned cDNA of cell-surface secreted forms of the glycoprotein of vesicular stomatitis virus in eucaryotic cells
April 1, 1982

Biosynthesis of lysosomal hydrolases: their synthesis in bound polysomes and the role of co- and post-translational processing in determining their subcellular distribution
1982

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter
September 1, 1982

Cell surface expression of the influenza virus hemagglutinin requires the hydrophobic carboxy-terminal sequences
April 1, 1983

Information within the mature LamB protein necessary for localization to the outer membrane of E coli K12
January 1, 1983

Membrane traffic in neurons and peptide-secreting cells
September 1, 1983

A subclass of proteins and sulfated macromolecules secreted by AtT-20 (mouse pituitary tumor) cells is sorted with adrenocorticotropin into dense secretory granules
March 1, 1983

Chloroquine diverts ACTH from a regulated to a constitutive secretory pathway in AtT-20 cells

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