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The factor V activation paradox

Published in: Journal of Biological Chemistry

Date of publication: February 24, 2004

Language: English

Bibliographic databases:

Cites articles 32

Date

Title

Authors

August 15, 1970

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
May 1, 1976

The mechanism of activation of bovine prothrombin by an activator isolated from Echis carinatus venon and characterization of the new active intermediates
January 1, 1976

Thrombin
September 1, 1977

Equilibria involved in prothrombin- and blood-clotting factor X-membrane binding
January 1, 1978

Geometric packing constraints in egg phosphatidylcholine vesicles
March 1, 1979

Interactions of a fluorescent active-site-directed inhibitor of thrombin: dansylarginine N-(3-ethyl-1,5-pentanediyl)amide
January 1, 1981

Isolation of functional human coagulation factor V by using a hybridoma antibody
November 1, 1981

Silver stain for proteins in polyacrylamide gels: a modified procedure with enhanced uniform sensitivity,Silver stain for proteins in polyacrylamide gels: A modified procedure with enhanced uniform sensitivity
May 1, 1982

Progressive development of a thrombin inhibitor binding site
July 1987

Complete cDNA and derived amino acid sequence of human factor V
February 1, 1990

Activation of human factor V by factor Xa and thrombin
June 1, 1992

Aminonaphthalenesulfonamides, a new class of modifiable fluorescent detecting groups and their use in substrates for serine protease enzymes
November 1, 1993

Cathepsin G activates human factor V in vitro
March 1, 1995

Thrombin-Catalyzed Activation of Recombinant Human Factor V
June 1, 1995

Evidence that meizothrombin is an intermediate product in the clotting of whole blood
August 1, 1997

Increased tissue factor-initiated prothrombin activation as a result of the Arg506 --> Gln mutation in factor VLEIDEN
August 1, 1997

Evaluation of the initiation phase of blood coagulation using ultrasensitive assays for serine proteases,Evaluation of the Initiation Phase of Blood Coagulation Using Ultrasensitive Assays for Serine Proteases
March 1, 1997

Functional characterization of recombinant human meizothrombin and Meizothrombin(desF1). Thrombomodulin-dependent activation of protein C and thrombin-activatable fibrinolysis inhibitor (TAFI), platelet aggregation, antithrombin-III inhibition
July 1, 1997

Cleavage requirements for activation of factor V by factor Xa,Cleavage Requirements for Activation of Factor V by Factor Xa
February 1, 1998

Autocatalytic peptide bond cleavages in prothrombin and meizothrombin
August 1, 1998

Proteolysis of factor V by cathepsin G and elastase indicates that cleavage at Arg1545 optimizes cofactor function by facilitating factor Xa binding,Proteolysis of Factor V by Cathepsin G and Elastase Indicates That Cleavage at Arg1545 Optimizes Cofactor Function by Facilitating Factor Xa Binding
May 1, 1999

A model describing the inactivation of factor Va by APC: bond cleavage, fragment dissociation, and product inhibition
October 15, 2001

Blood coagulation at the site of microvascular injury: effects of low-dose aspirin

,
February 14, 2001

The role of the membrane in the inactivation of factor va by plasmin. Amino acid region 307-348 of factor V plays a critical role in factor Va cofactor function
March 13, 2002

A model for the stoichiometric regulation of blood coagulation
December 20, 2002

Analysis of the kinetics of prothrombin activation and evidence that two equilibrating forms of prothrombinase are involved in the process
July 1, 2002

Thrombin functions during tissue factor-induced blood coagulation
August 5, 2002

Thrombin-mediated proteolysis of factor V resulting in gradual B-domain release and exposure of the factor Xa-binding site
January 1, 2003

The dynamics of thrombin formation
January 1, 2003

Factor V: a combination of Dr Jekyll and Mr Hyde
June 4, 2003

Structural requirements for expression of factor Va activity
May 1, 2003

Predicting the pharmacology of thrombin inhibitors

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