David W. Hein

country of citizenship: United States of America

David W. Hein is an American professor and scientist. He currently is a Distinguished University Scholar at the University of Louisville where he serves as the Peter K. Knoefel Endowed Chair of Pharmacology and Professor & Chair of the Department of Pharmacology & Toxicology. Source: Wikipedia (en)

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Articles 170

Date

Title

Authors

2023-07

Induction of glucose production by heterocyclic amines is dependent on N-acetyltransferase 2 genetic polymorphism in cryopreserved human hepatocytes

David W. Hein
2023-05-29

N-acetyltransferase 2 haplotype modifies risks for both dyslipidemia and urinary bladder cancer

David W. Hein
2023-06

Effect of N-acetyltransferase 2 genetic polymorphism on 4,4'-methylenebis(2-chloroaniline)-induced genotoxicity and oxidative stress

David W. Hein
2023-06

Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity

David W. Hein
2023

Non-coding and intergenic genetic variants of human arylamine -acetyltransferase 2 (NAT2) gene are associated with differential plasma lipid and cholesterol levels and cardiometabolic disorders

David W. Hein
2023-06

Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes

David W. Hein
2023-03-31

Stable Isotope Tracing Reveals an Altered Fate of Glucose in -Acetyltransferase 1 Knockout Breast Cancer Cells

Xiang Zhang, David W. Hein
2023-07

Upregulation of cytidine deaminase in NAT1 knockout breast cancer cells

David W. Hein
2023-01

N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances

David W. Hein
2022

Association between cigarette smoking and ovarian reserve among women seeking fertility care

David W. Hein
2022

Acetyl coenzyme A kinetic studies on -acetylation of environmental carcinogens by human -acetyltransferase 1 and its variant

David W. Hein
2022-11-23

Transcriptional Regulation of Human Arylamine N-Acetyltransferase 2 Gene by Glucose and Insulin in Liver Cancer Cell Lines

David W. Hein
2022-12

N-acetyltransferase 2 acetylator genotype-dependent N-acetylation and toxicity of the arylamine carcinogen β-naphthylamine in cryopreserved human hepatocytes

David W. Hein
2022-12

Dataset for proteomic analysis of arylamine -acetyltransferase 1 knockout MDA-MB-231 breast cancer cells

David W. Hein
2022-11

Differences in β-naphthylamine metabolism and toxicity in Chinese hamster ovary cell lines transfected with human CYP1A2 and NAT2*4, NAT2*5B or NAT2*7B N-acetyltransferase 2 haplotypes

David W. Hein
2022

Proteomic analysis of arylamine -acetyltransferase 1 knockout breast cancer cells: Implications in immune evasion and mitochondrial biogenesis

David W. Hein
2022-08-15

Hexavalent chromium increases the metabolism and genotoxicity of aromatic amine carcinogens 4-aminobiphenyl and β-naphthylamine in immortalized human lung epithelial cells

David W. Hein
2022-05-01

Expression of arylamine N-acetyltransferase 2 activity in immortalized human bronchial epithelial cells

David W. Hein
2022

Human -Acetyltransferase 1 and 2 Differ in Affinity Towards Acetyl-Coenzyme A Cofactor and -Hydroxy-Arylamine Carcinogens

David W. Hein
2022

560G>A (rs4986782) (R187Q) Single Nucleotide Polymorphism in Arylamine N-Acetyltransferase 1 Increases Affinity for the Aromatic Amine Carcinogens 4-Aminobiphenyl and N-Hydroxy-4-Aminobiphenyl: Implications for Cancer Risk Assessment

David W. Hein
2022-05

Deletion of arylamine N-acetyltransferase 1 in MDA-MB-231 human breast cancer cells reduces primary and secondary tumor growth in vivo with no significant effects on metastasis

David W. Hein
2022

Arylamine -Acetyltransferase 1 Activity is Regulated by the Protein Acetylation Status

David W. Hein
2022-02

Identification and characterization of potent, selective, and efficacious inhibitors of human arylamine N-acetyltransferase 1

David W. Hein
2021-01-01

Human Arylamine <i>N</i>-Acetyltransferase 1 (NAT1) Knockout in MDA-MB-231 Breast Cancer Cell Lines Leads to Transcription of NAT2

David W. Hein, Patrick J Trainor
2020-04-01

N-acetyltransferase 2 acetylator genotype-dependent N-acetylation of 4-aminobiphenyl in cryopreserved human hepatocytes

David W. Hein
2020-05-05

Human arylamine N-acetyltransferase 2 genotype-dependent protein expression in cryopreserved human hepatocytes

David W. Hein
2020-06-17

CRISPR/Cas9 knockout of human arylamine N-acetyltransferase 1 in MDA-MB-231 breast cancer cells suggests a role in cellular metabolism

David W. Hein, Samantha M Carlisle, Patrick J Trainor
2020-09-28

Acetylator Genotype-Dependent Dyslipidemia in Rats Congenic for N-Acetyltransferase 2

David W. Hein, Gavin E Arteel
2020-10-23

Arylamine N-acetyltransferase acetylation polymorphisms: paradigm for pharmacogenomic-guided therapy- a focused review

David W. Hein
2020-11-02

Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes

J C States, David W. Hein
2019-08-20

N-Acetyltransferase 1 Knockout Elevates Acetyl Coenzyme A Levels and Reduces Anchorage-Independent Growth in Human Breast Cancer Cell Lines

David W. Hein
2019-07-10

Role of the human N-acetyltransferase 2 genetic polymorphism in metabolism and genotoxicity of 4, 4'-methylenedianiline

David W. Hein

Human - wd:Q5240706

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