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Presenilin 1 and cadherins: stabilization of cell-cell adhesion and proteolysis-dependent regulation of transcription.

Author

Spiros Efthimiopoulos

published in: Neurodegenerative Diseases

date of publication: 2004-01-01

main subject: proteolýza, cell adhesion

Bibliographic databases:

Cites articles 55

Date

Title

Authors

1987-02

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
1991-07-01

Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells
1992-12-01

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production
1992-09-01

Amyloid beta-peptide is produced by cultured cells during normal metabolism
1994

Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease
1994-01-01

Involvement of amyloid as a central step in the development of Alzheimer's disease
1995-06-29

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

,
1996-08

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

,
1996-11-01

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo
1996-10-01

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

,
1996-08-01

Expression and analysis of presenilin 1 in a human neuronal system: localization in cell bodies and dendrites
1996-08-15

Functional interaction of beta-catenin with the transcription factor LEF-1
1997-03-01

The Alzheimer family of diseases: many etiologies, one pathogenesis?
1997-01

Presenilin Proteins Undergo Heterogeneous Endoproteolysis between Thr291and Ala299and Occur as Stable N- and C-Terminal Fragments in Normal and Alzheimer Brain Tissue

, ,
1997-02-01

Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins.
1997-11-01

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
1998-10-01

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor
1998-02-01

The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex
1998-11-01

Effects of PS1 deficiency on membrane protein trafficking in neurons
1998-01-01

Alzheimer's disease: a re-examination of the amyloid hypothesis
1999-03-30

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease
1999-04-08

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity
1999-12-01

Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts
2000-06-08

Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1
2000-07-01

Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.
2000-09-01

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

, ,
2000-11-13

Cleavage and shedding of E-cadherin after induction of apoptosis
2000-02-01

Truncation of the beta-catenin binding domain of E-cadherin precedes epithelial apoptosis during prostate and mammary involution
2001-09

Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch
2001-02-01

Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex
2001-12-10

Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4
2001-11-19

Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway

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