Anna Maria Caccuri
occupation: researcher
Articles 49
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Glutathione transferase P silencing promotes neuronal differentiation of retinal R28 cells
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Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis
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A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib
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Nitrobenzoxadiazole-based GSTP1-1 inhibitors containing the full peptidyl moiety of (pseudo)glutathione
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Synthesis and structure--activity relationship of new cytotoxic agents targeting human glutathione-S-transferases
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Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines.
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Characterization of a new trabectedin-resistant myxoid liposarcoma cell line that shows collateral sensitivity to methylating agents.
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The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.
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Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: a promising therapeutic strategy.
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Role of glutathione transferases in the mechanism of brostallicin activation.
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Overcoming resistance to conventional drugs in Ewing sarcoma and identification of molecular predictors of outcome
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6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol, a specific glutathione S-transferase inhibitor, overcomes the multidrug resistance (MDR)-associated protein 1-mediated MDR in small cell lung cancer.
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Modulation of the GSTT1 activity by the GSTM1 phenotype in a sample of Italian farm-workers.
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Overcoming glutathione S-transferase P1-related cisplatin resistance in osteosarcoma.
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A strong glutathione S-transferase inhibitor overcomes the P-glycoprotein-mediated resistance in tumor cells. 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) triggers a caspase-dependent apoptosis in MDR1-expressing leukemia cells.
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Glutathione transferases sequester toxic dinitrosyl-iron complexes in cells. A protection mechanism against excess nitric oxide
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Nitrosylation of human glutathione transferase P1-1 with dinitrosyl diglutathionyl iron complex in vitro and in vivo
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Cooperativity and pseudo-cooperativity in the glutathione S-transferase from Plasmodium falciparum.
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Potent isozyme-selective inhibition of human glutathione S-transferase A1-1 by a novel glutathione S-conjugate.
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Binding and kinetic mechanisms of the Zeta class glutathione transferase
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The specific interaction of dinitrosyl-diglutathionyl-iron complex, a natural NO carrier, with the glutathione transferase superfamily: suggestion for an evolutionary pressure in the direction of the storage of nitric oxide
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Glutathione transferase P1-1: self-preservation of an anti-cancer enzyme
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Synthesis and activity of novel glutathione analogues containing an urethane backbone linkage.
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GSTB1-1 from Proteus mirabilis: a snapshot of an enzyme in the evolutionary pathway from a redox enzyme to a conjugating enzyme
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Properties and utility of the peculiar mixed disulfide in the bacterial glutathione transferase B1-1.
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Human glutathione transferase T2-2 discloses some evolutionary strategies for optimization of the catalytic activity of glutathione transferases.
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Valine 10 May Act as a Driver for Product Release from the Active Site of Human Glutathione Transferase P1-1
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Temperature adaptation of glutathione S-transferase P1-1. A case for homotropic regulation of substrate binding.
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Mutations of Gly to Ala in human glutathione transferase P1-1 affect helix 2 (G-site) and induce positive cooperativity in the binding of glutathione.
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Shifting Substrate Specificity of Human Glutathione Transferase (from Class Pi to Class Alpha) by a Single Point Mutation
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Solution Structure of Glutathione Bound to Human Glutathione Transferase P1-1: Comparison of NMR Measurements with the Crystal Structure†
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Proton release upon glutathione binding to glutathione transferase P1-1: kinetic analysis of a multistep glutathione binding process
Human - wd:Q56926968