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Conditional gene targeting

Author

Jürgen Roes

Klaus Rajewsky

Werner Müller

Published in: Journal of Clinical Investigation

Date of publication: August 1, 1996

Language: English

Main subject: gene targeting

Bibliographic databases:

Cites articles 30

Date

Title

Authors

August 25, 1981

Bacteriophage P1 site-specific recombination. I. Recombination between loxP sites
June 1, 1982

P1 site-specific recombination: nucleotide sequence of the recombining sites
April 1, 1983

Studies on the properties of P1 site-specific recombination: evidence for topologically unlinked products following recombination,Studies on the properties of P1 site-specific recombination: Evidence for topologically unlinked products following recombination
September 1, 1984

Site-specific recombination by the bacteriophage P1 lox-Cre system. Cre-mediated synapsis of two lox sites
February 1, 1986

The integrase family of site-specific recombinases: regional similarities and global diversity
November 6, 1987

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
July 1988

Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1
March 1, 1989

The new mouse genetics: altering the genome by gene targeting
March 1, 1991

Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells
March 1, 1991

Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells

, ,
July 15, 1992

Targeted oncogene activation by site-specific recombination in transgenic mice
January 1, 1992

Altering genes in animals by gene targeting
August 1, 1992

Tissue- and site-specific DNA recombination in transgenic mice
June 18, 1993

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
February 1, 1994

Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice
March 1, 1994

Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells
July 1, 1994

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
September 1, 1994

Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter
December 1, 1994

Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies

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December 1, 1995

T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination
December 25, 1995

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

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September 1, 1995

Inducible gene targeting in mice
August 4, 1995

Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2
July 1, 1995

Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase

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July 1, 1995

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice

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December 1, 1995

Chromosome engineering in mice
April 1, 1996

Efficient control of gene expression by single step integration of the tetracycline system in transgenic mice
April 1, 1996

Regulation of Cre recombinase activity by the synthetic steroid RU 486.
February 1, 1996

Inducible site-directed recombination in mouse embryonic stem cells
June 1, 1996

Aberrant B cell development and immune response in mice with a compromised BCR complex

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