Nunilo Cremades

1979 -

country of citizenship: Spain

languages spoken, written or signed: Spanish, English

Nunilo Cremades Casasín (Barbastro, 1979) es una investigadora española, doctora en ciencias y biofísica, especializada en la investigación de enfermedades neurodegenarativas como el Parkinson. Fue reconocida con el Premio Enrique Pérez Payá SBE-40 de la Sociedad de Biofísica de España, el mayor reconocimiento en el campo de la biofísica en España.[1][2] Source: Wikipedia (es)

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Articles 31

Date

Title

Authors

2021-03-22

The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells

Roberta Cascella, Alessandra Bigi, Catherine Xu, Chris Dobson, Fabrizio Chiti, Nunilo Cremades, Cristina Cecchi
2020-08-13

Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism

Benedetta Mannini, Francesco Simone Ruggeri, Roberta Cascella, Michele Perni, Alessandra Bigi, Janet R Kumita, Nunilo Cremades, Cristina Cecchi, Tuomas Knowles, Michele Vendruscolo, Chris Dobson
2020-10-28

Multiplicity of α-Synuclein Aggregated Species and Their Possible Roles in Disease

Nunilo Cremades
2019-11-18

Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions

Nunilo Cremades, David A Agard, Eliezer Masliah
2018-06-28

Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine

Michele Perni, Patrick Flagmeier, Ryan Limbocker, Francesco Antonio Aprile, Celine Galvagnion, Gabriella Heller, Georg Meisl, Janet R Kumita, Pavan Kumar Challa, Julius B. Kirkegaard, Benedetta Mannini, Cristina Cecchi, Nunilo Cremades, Tuomas Knowles, Fabrizio Chiti, Michele Vendruscolo, Chris Dobson, Serene W Chen, Roberta Cascella, Ellen A A Nollen
2017-01-17

A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity

Celine Galvagnion, Georg Meisl, Julius B. Kirkegaard, Patrick Flagmeier, Serene W Chen, Ryan Limbocker, Pietro Sormanni, Gabriella Heller, Francesco Antonio Aprile, Cristina Cecchi, Tuomas Knowles, Michele Vendruscolo, Nunilo Cremades, Chris Dobson, Roberta Cascella, Ellen A A Nollen
2017-12-01

Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers.

Roberta Cascella, Liming Ying, Giuliana Fusco, Serene W Chen, Philip Williamson, Michele Perni, Cristina Cecchi, Michele Vendruscolo, Fabrizio Chiti, Nunilo Cremades, Chris Dobson, Alfonso De Simone
2015-04-08

Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation

David Klenerman, Serene W Chen, Francesco Antonio Aprile, Cintia Roodveldt, Nicholas W. Wood, Tuomas Knowles, Carlos Alfonso, German Rivas, Andrey Y Abramov, José María Valpuesta, Nunilo Cremades, Chris Dobson, Erwin J De Genst
2015-08-10

Fast flow microfluidics and single-molecule fluorescence for the rapid characterization of α-synuclein oligomers

David Klenerman, Alexander J Dear, Laura Tosatto, Nunilo Cremades, Mauro Dalla Serra, Chris Dobson, Tuomas Knowles, Marija Iljina, Mathew H Horrocks
2015-11-19

Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson's disease genetically related mutants

David Klenerman, Alexander J Dear, Laura Tosatto, Nunilo Cremades, Mauro Dalla Serra, Chris Dobson, Tuomas Knowles, Mathew H Horrocks
2015-08-06

Cell surface localised Hsp70 is a cancer specific regulator of clathrin-independent endocytosis

Benedikt Nimmervoll, Johannes Preiner, Nunilo Cremades, Francesco Antonio Aprile, Lilia A. Chtcheglova, Peter Hinterdorfer
2015-11-12

Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease

David Klenerman, Blerida Banushi, Serene W Chen, Nunilo Cremades, Michael J Devine, Andrey Y Abramov, Nicholas W. Wood, Paul Gissen, Chris Dobson, Marthe H Ludtmann, Mathew H Horrocks, Sonia Gandhi, Plamena R Angelova
2014

Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease

Jennifer A. Johnston, Nunilo Cremades, Celine Galvagnion, Alexander K Buell, Chris Dobson, Michele Vendruscolo, Mitali A Tambe, Tuomas Knowles, Carlos W. Bertoncini, Dale Schenk
2013-06-28

Hsp70 oligomerization is mediated by an interaction between the interdomain linker and the substrate-binding domain

Chris Dobson, Florian Stengel, Nunilo Cremades, Francesco Antonio Aprile, Cintia Roodveldt, Xavier Salvatella, Paolo Tortora, Carol V. Robinson, Justin L.P. Benesch, Anne Dhulesia
2013-04-01

Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages

Alexander K Buell, Francesco Antonio Aprile, Elin K. Esbjörner, Michele Vendruscolo, Nunilo Cremades, Els Pardon, Jan Steyaert, Lode Wyns, Chris Dobson, Erwin J De Genst, Tim Guilliams
2012-05-01

Direct observation of the interconversion of normal and toxic forms of α-synuclein

David Klenerman, Nunilo Cremades, Andrey Y Abramov, Allen Y Chen, Angel Orte, Massimo Sandal, Richard W Clarke, Francesco Antonio Aprile, Carlos W. Bertoncini, Nicholas W. Wood, Tuomas Knowles, Chris Dobson
2012-01

Insights in the (un)structural organization of Bacillus pasteurii UreG, an intrinsically disordered GTPase enzyme

Vladimir Uversky, Nunilo Cremades, Paolo Neyroz, Paola Turano, Stefano Ciurli
2011-04-29

Population of nonnative states of lysozyme variants drives amyloid fibril formation

Alexander K Buell, Xavier Salvatella, Chris Dobson, Maria F Mossuto, Nunilo Cremades, Tuomas Knowles, Anne Dhulesia, Janet R Kumita
2010-09-17

Structure and properties of a complex of α-synuclein and a single-domain camelid antibody

Jan Steyaert, Els Pardon, Nunilo Cremades, Christopher A Waudby, Shang-Te Danny Hsu, Chris Dobson, Lode Wyns, Erwin J De Genst, Tim Guilliams
2010-11-01

Local cooperativity in an amyloidogenic state of human lysozyme observed at atomic resolution

Maria F Mossuto, Nunilo Cremades, Xavier Salvatella, Daniel Nietlispach, Shang-Te Danny Hsu, Chris Dobson, Anne Dhulesia, Janet R Kumita
2009-11-01

Discovery of specific flavodoxin inhibitors as potential therapeutic agents against Helicobacter pylori infection

Marta Martínez-Júlvez, Nunilo Cremades, Adrian Velazquez-campoy, Juan A Hermoso, Javier Sancho, Angel Lanas
2009-09-01

On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of alpha-synuclein with Congo red and lacmoid

Carlos W. Bertoncini, Nunilo Cremades, Christofer Lendel, Christopher A Waudby, Michele Vendruscolo, Chris Dobson, Dale Schenk
2008-08-01

Identification of pharmacological chaperones as potential therapeutic agents to treat phenylketonuria

Nunilo Cremades, Angel L. Pey, Aurora Martinez, Adrian Velazquez-campoy
2008-04-25

Molten globule and native state ensemble of Helicobacter pylori flavodoxin: can crowding, osmolytes or cofactors stabilize the native conformation relative to the molten globule?

Nunilo Cremades, Javier Sancho
2007-11-01

Common conformational changes in flavodoxins induced by FMN and anion binding: the structure of Helicobacter pylori apoflavodoxin

Marta Martínez-Júlvez, Nunilo Cremades, Celia M Maya, Santiago Cuesta-López, Fernando Falo, Juan A Hermoso, Javier Sancho
2007-04-27

Flavodoxin:quinone reductase (FqrB): a redox partner of pyruvate:ferredoxin oxidoreductase that reversibly couples pyruvate oxidation to NADPH production in Helicobacter pylori and Campylobacter jejuni

Matthew A Croxen, Nunilo Cremades
2007-12-21

The flavodoxin from Helicobacter pylori: structural determinants of thermostability and FMN cofactor binding

Nunilo Cremades, Adrian Velazquez-campoy, Javier Sancho
2007-11-11

Conformational stability of Helicobacter pylori flavodoxin: fit to function at pH 5

Adrian Velazquez-campoy, Nunilo Cremades, Javier Sancho
2006-12-11

Antiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni

Michael G Morash, Matthew A Croxen, Nunilo Cremades
2006-07-25

The native-state ensemble of proteins provides clues for folding, misfolding and function

Nunilo Cremades, Javier Sancho
2005-01-07

Towards a new therapeutic target: Helicobacter pylori flavodoxin

Nunilo Cremades, Javier Sancho

Human - wd:Q57238670

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