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Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2

Published in: The Journal of Neuroscience

Date of publication: July 1, 1996

Main subject: retinal ganglion cell, cell death

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Cites articles 43

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Authors

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Neuronal and neuroglial responses following retinal lesions in the neonatal rats
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Evidence for an amacrine cell system in the ganglion cell layer of the rat retina
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Postnatal changes in retinal ganglion cell and optic axon populations in the pigmented rat.
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Immunohistochemical localization of a macrophage-specific antigen in developing mouse retina: phagocytosis of dying neurons and differentiation of microglial cells to form a regular array in the plexiform layers
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Cell death during differentiation of the retina in the mouse
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Major role for neuronal death during brain development: refinement of topographical connections
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Schwann cells promote the survival of rat retinal ganglion cells after optic nerve section
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Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: Evidence for the role of cell death genes
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The pearl mutation accelerates the schedule of natural cell death in the early postnatal retina
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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
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Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene
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Social controls on cell survival and cell death
March 1, 1993

The protooncogene bcl-2 inhibits apoptosis in PC12 cells
February 1, 1993

Treatment of the adult retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro
January 1, 1993

Molecular mechanisms of developmental neuronal death
October 22, 1993

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

,
February 1, 1993

Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo
October 1, 1993

In situ labeling of granule cells for apoptosis-associated DNA fragmentation reveals different mechanisms of cell loss in developing cerebellum
April 1, 1993

The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
April 1, 1994

Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death
December 1, 1994

Nerve growth factor reduces apoptosis of axotomized retinal ganglion cells in the neonatal rat
July 1, 1994

Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats
October 1, 1994

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

,
April 1, 1994

Regeneration of lesioned rat optic nerve fibers is improved after neutralization of myelin-associated neurite growth inhibitors

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