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Editions published in Chemistry and Biology 3337
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Stabilizing effects of the RNA 2′-substituent: crystal structure of an oligodeoxynucleotide duplex containing 2′-O-methylated adenosines
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Atomic structure of the trypsin-A90720A complex: a unified approach to structure and function
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A DNA enzyme that cleaves RNA
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Conformation of a water-soluble derivative of taxol in water by 2D-NMR spectroscopy
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The effects of N7-methylguanine on duplex DNA structure
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Synthetic calicheamicin mimics with novel initiation mechanisms: DNA cleavage, cytotoxicity, and apoptosis
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From genetics to chemistry: tumor suppressor genes and drug discovery
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The terpenoid theory of the origin of cellular life: the evolution of terpenoids to cholesterol
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Targeting the glycosaminoglycan-binding sites on proteins
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Falling out of the fold: tumorigenic mutations and p53
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Synthetic and biological catalysts in chemical synthesis: how to assess practical utility
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Making agonists of antagonists
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Proximity versus allostery: the role of regulated protein dimerization in biology
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Why we live and why we die
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Cyclin-dependent kinases: regulators of the cell cycle and more
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Proteasomes: the changing face of proteolysis
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Anti-malarial drug development using models of enzyme structure
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Structural model of antagonist and agonist binding to the angiotensin II, AT1 subtype, G protein coupled receptor
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Tilted amides in amino acid and peptide derivatives
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Magnetic circular dichroism studies of exogenous ligand and substrate binding to the non-heme ferrous active site in phthalate dioxygenase
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Genetically engineered synthesis of precorrin-6x and the complete corrinoid, hydrogenobyrinic acid, an advanced precursor of vitamin B12
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Free radicals, peroxides and the control of gene expression
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DNA binding by an amino acid residue in the C-terminal half of the Rel homology region
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Towards a pharmacological genetics
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Engineered biosynthesis of novel polyketides: evidence for temporal, but not regiospecific, control of cyclization of an aromatic polyketide precursor
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Engineering an interfacial zinc site to increase hormone-receptor affinity
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Distinct binding and cellular properties of synthetic (+)- and (-)-discodermolides
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Metal-coordination sphere in the methylated Ada protein-DNA co-complex
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The phosphopeptide-binding specificity of Src family SH2 domains
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Mechanistic studies of a signaling pathway activated by the organic dimerizer FK1012
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Distribution of labor among bZIP segments in the control of DNA affinity and specificity
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Flux of intracellular labile zinc during apoptosis (gene-directed cell death) revealed by a specific chemical probe, Zinquin
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