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Nature Methods is a monthly peer-reviewed scientific journal covering new scientific techniques. It was established in 2004 and is published by Springer Nature under the Nature Portfolio. Like other Nature journals, there is no external editorial board and editorial decisions are made by an in-house team, although peer review by external experts forms a part of the review process. The editor-in-chief is Allison Doerr. Every year, the journal highlights a field, approach, or technique that has enabled recent major advances in life sciences research as the "Method of the Year". According to the Journal Citation Reports, the journal had a 2021 impact factor of 47.990, ranking it first in the category "Biochemical Research Methods". Source: Wikipedia (en)
Editions published in Nature Methods 4565
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Identifying and quantifying in vivo methylation sites by heavy methyl SILAC
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Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas
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A rapid method for determining protein kinase phosphorylation specificity
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Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis
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Simultaneous, coincident optical trapping and single-molecule fluorescence
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Automated approach for quantitative analysis of complex peptide mixtures from tandem mass spectra
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RNAi living-cell microarrays for loss-of-function screens in Drosophila melanogaster cells.
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Three-chromophore FRET microscopy to analyze multiprotein interactions in living cells
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Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo
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Strategies for the reconstitution of chromatin.
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Large-scale database searching using tandem mass spectra: looking up the answer in the back of the book
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LAMP, a new imaging assay of gap junctional communication unveils that Ca2+ influx inhibits cell coupling
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High-throughput localization of functional elements by quantitative chromatin profiling
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Real-time monitoring of ubiquitination in living cells by BRET.
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Polyene-lipids: a new tool to image lipids
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A custom microarray platform for analysis of microRNA gene expression
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Genotyping over 100,000 SNPs on a pair of oligonucleotide arrays.
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A highly informative SNP linkage panel for human genetic studies.
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In vitro selection and prediction of TIP47 protein-interaction interfaces
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Using protein-DNA chimeras to detect and count small numbers of molecules
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Detecting protein-protein interactions with GFP-fragment reassembly.
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Microarray-based, high-throughput gene expression profiling of microRNAs
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Use of quantum dots for live cell imaging.
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Exploiting the 21st amino acid-purifying and labeling proteins by selenolate targeting.
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5,000 RNAi experiments on a chip.
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LigAmp for sensitive detection of single-nucleotide differences.
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Hybridization chain reaction
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Methods for methods' sake
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Cloning of short hairpin RNAs for gene knockdown in mammalian cells.
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Preparation, isolation and characterization of stage-specific spermatogenic cells for cellular and molecular analysis
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SNPs made routine
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Novel at the library
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