Evert J Homan

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Artikler 16

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2020-06-22

Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target

Petra Marttila, Ann-Sofie Jemth, Pål Stenmark, Evert J Homan, Judith E Unterlass
2020-07-20

Development of a chemical probe against NUDT15

Si Min Zhang, Matthieu Desroses, Daniel Rehling, Thomas Lundbäck, Hanna Axelsson, Torsten Schaller, Saeed Eshtad, Mikael Altun, Sean G Rudd, Stefan Knapp, Ulrika Warpman Berglund, Pål Stenmark, Olov A Wallner, Evert J Homan, Linda Pudelko, Juliane Kutzner, Christina Kalderén, Shruti Regmi, Adam Throup, Lars Bräutigam
2018-01-17

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.

Pål Stenmark, Nicholas Valerie, Roni H. G. Wright, Olov A Wallner, Rebecka Isaksson, Sean G Rudd, Ann-Sofie Jemth, Sabin Llona-Minguez, Anna-Lena Gustavsson, Thomas Lundbäck, Evert J Homan, Pawel Baranczewski, Ingrid Almlöf, Fredrik Jeppsson, Martin Scobie, Kia Strömberg, Hanna Axelsson, Shruti Regmi
2018-11-01

MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP

Ann-Sofie Jemth, Robert Gustafsson, Antonio Sarno, Ulrika Warpman Berglund, Pål Stenmark, Linda Henriksson, Evert J Homan, Lars Bräutigam, Ingrid Almlöf, Azita Rasti
2018-11-01

Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Torkild Visnes, Armando Cázares-Körner, Wenjing Hao, Olov A Wallner, Geoffrey Masuyer, Antonio Sarno, Juan Astorga-Wells, Ann-Sofie Jemth, Stella Karsten, Bishoy M F Hanna, Cynthia B J Paulin, Dag Ivanic, Petar Iliev, Martin Scobie, Per Artursson, Mikael Altun, Xueqing Ba, Roman Zubarev, Pål Stenmark, Thomas Helleday, Hans Einar Krokan, Tobias Koolmeister, Pawel Baranczewski, Evert J Homan, Therese Pham, Annika Jenmalm-Jensen, Ulrika Warpman Berglund, Azita Rasti, Elisee Wiita, Oliver Mortusewicz, Christina Kalderén
2017-05-16

Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors

Sabin Llona-Minguez, Matthieu Desroses, José Manuel Calderón-Montaño, Estefanía Burgos Morón, Nicholas Valerie, André Mateus, Amir Mehdizadeh, Ann-Sofie Jemth, Ulrika Warpman Berglund, Thomas Lundbäck, Thomas Helleday, Evert J Homan, Andreas Höglund, Pawel Baranczewski, Elisee Wiita, Ingrid Almlöf, Kristmundur Sigmundsson, Annika Jenmalm-Jensen, Per Artursson, Martin Scobie, Artin Ghassemian, Tobias Koolmeister, Cindy Cazares-Körner, Masoud Darabi, Shabnam Fayezi
2017-04-01

dUTPase inhibition augments replication defects of 5-Fluorouracil

Matthieu Desroses, Thomas Helleday, Antonio Sarno, Ann-Sofie Jemth, Thomas Lundbäck, Anna-Lena Gustavsson, Evert J Homan, Ingrid Almlöf, Martin Scobie, Elisee Wiita, Oliver Mortusewicz, Cynthia B J Paulin, Anna Hagenkort, Tobias Koolmeister
2017-04-01

Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Ronnie Berntsson, Robert Gustafsson, Helge Gad, Thomas Lundbäck, Ann-Sofie Jemth, Pål Stenmark, Christina Kalderén, Roger Olofsson Bagge, Fabienne Z Gaugaz, Olov A Wallner, Tobias Koolmeister, Saeed Eshtad, Linda Elfsmark, Aljona Saleh, Camilla Göktürk, Pawel Baranczewski, Richard Svensson, Kia Strömberg, Marie-Caroline Jacques-Cordonnier, Evert J Homan, Lars Bräutigam, Andreas Höglund, Anna Hagenkort, Therese Pham, Svante Vikingsson, Bastiaan Evers, Martin Henriksson, Lars G. J. Hammarström, Elisee Wiita, Ingrid Almlöf, Tatjana Djureinovic, Jordi Carreras-Puigvert, Maria Häggblad, Fredrik Jeppsson, Ulf Martens, Cecilia Lundin, Ingrid Granelli, Annika Jenmalm-Jensen, Per Artursson, Martin Scobie, Matthieu Desroses, Hanna Axelsson
2017-09-20

Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space.

Thomas Helleday, Pål Stenmark, Jens Carlsson, Robert Gustafsson, Ulrika Warpman Berglund, Evert J Homan, Ingrid Almlöf, Martin Scobie
2017-09-01

Correction to Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors.

Thomas Helleday, Sabin Llona-Minguez, Estefanía Burgos Morón, Thomas Lundbäck, Ann-Sofie Jemth, Evert J Homan, Andreas Höglund, Pawel Baranczewski, Elisee Wiita, Ingrid Almlöf, Kristmundur Sigmundsson, Annika Jenmalm-Jensen, Per Artursson, Ulrika Warpman Berglund, Martin Scobie, José Manuel Calderón-Montaño, Nicholas Valerie, Artin Ghassemian, Tobias Koolmeister, Cindy Cazares-Körner, Masoud Darabi, Shabnam Fayezi, Matthieu Desroses
2017-02-01

Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.

Thomas Helleday, Sabin Llona-Minguez, André Mateus, José Manuel Calderón-Montaño, Ann-Sofie Jemth, Thomas Lundbäck, Ulrika Warpman Berglund, Evert J Homan, Andreas Höglund, Pawel Baranczewski, Elisee Wiita, Ingrid Almlöf, Annika Jenmalm-Jensen, Per Artursson, Martin Scobie, Maria Häggblad, Cindy Cazares-Körner, Ulf Martens
2017-09-01

Novel spirocyclic systems via multicomponent aza-Diels-Alder reaction

Pål Stenmark, Thomas Helleday, Adam Throup, Evert J Homan, Sabin Llona-Minguez, Annika Jenmalm-Jensen
2016-02-09

Hypoxic Signaling and the Cellular Redox Tumor Environment Determine Sensitivity to MTH1 Inhibition

Thomas Helleday, Pål Stenmark, Ann-Sofie Jemth, Robert Gustafsson, Carsten Berndt, Evert J Homan, Lars Bräutigam, Jordi Carreras-Puigvert, Ulrika Warpman Berglund, Linda Pudelko
2016-08-16

NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine

Pål Stenmark, Ann-Sofie Jemth, Nicholas Valerie, Geoffrey Masuyer, Patrick Herr, Evert J Homan, Anna Hagenkort, Luka Bevc
2016-11-29

Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor.

Pål Stenmark, Ann-Sofie Jemth, Thomas Helleday, Evert J Homan, Sabin Llona-Minguez, Elisee Wiita, Maria Häggblad
2014-04-10

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Thomas Helleday, Pål Stenmark, Ann-Sofie Jemth, Fabienne Z Gaugaz, Berglind O Einarsdottir, Robert Gustafsson, Hanna Axelsson, Helge Gad, Olov A Wallner, Ronnie Berntsson, Matthieu Desroses, Roger Olofsson Bagge, Mikael Altun, Thomas Lundbäck, Christina Kalderén, Martin Scobie, Anna-Lena Gustavsson, Ulrika Warpman Berglund, Tobias Koolmeister, Saeed Eshtad, Linda Elfsmark, Aljona Saleh, Camilla Göktürk, Pawel Baranczewski, Richard Svensson, Kia Strömberg, Marie-Caroline Jacques-Cordonnier, Evert J Homan, Lars Bräutigam, Andreas Höglund, Anna Hagenkort, Therese Pham, Svante Vikingsson, Bastiaan Evers, Martin Henriksson, Lars G. J. Hammarström, Elisee Wiita, Ingrid Almlöf, Tatjana Djureinovic, Jordi Carreras-Puigvert, Maria Häggblad, Fredrik Jeppsson, Ulf Martens, Cecilia Lundin, Ingrid Granelli, Annika Jenmalm-Jensen, Per Artursson

Human - wd:Q114444840

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