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Molecular imaging in drug development

author

Juergen K Willmann

published in: Nature Reviews Drug Discovery

date of publication: 2008-07-01

language: English

main subject: molecular imaging

Cites articles 134

Date

Title

Authors

2008-01-01

Molecular imaging of the efficacy of heat shock protein 90 inhibitors in living subjects

Gabriela Chiosis
2008-01-16

Patterns of alphavbeta3 expression in primary and metastatic human breast cancer as shown by 18F-Galacto-RGD PET.

Markus Schwaiger
2008-01-07

US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice

Xiaoyuan Chen
2008-08-11

Targeted microbubbles for imaging tumor angiogenesis: assessment of whole-body biodistribution with dynamic micro-PET in mice

Juergen K Willmann
2007-01-24

Reporter gene imaging of protein-protein interactions in living subjects
2007-02-13

Combinatorial library screening for developing an improved split-firefly luciferase fragment-assisted complementation system for studying protein-protein interactions
2007-01-01

Current state of imaging protein-protein interactions in vivo with genetically encoded reporters

David Piwnica-Worms
2007-08-01

An improved bioluminescence resonance energy transfer strategy for imaging intracellular events in single cells and living subjects

Andreas Loening
2007-12-12

Comparison of integrin alphaVbeta3 expression and glucose metabolism in primary and metastatic lesions in cancer patients: a PET study using 18F-galacto-RGD and 18F-FDG.

Markus Schwaiger
2007-01-01

Monitoring response to anticancer therapy by targeting microbubbles to tumor vasculature

Paul A Grayburn, Jason Fleming
2006-10-16

An intramolecular folding sensor for imaging estrogen receptor-ligand interactions
2006-07-01

The added value of metabolic imaging with FDG-PET in oesophageal cancer: prognostic role and prediction of response to treatment
2006-03-20

The prognostic value of positron emission tomography in non-small cell lung cancer: analysis of 266 cases.

Wendy J Post
2006-03-01

Positron-emission tomography as a prognostic tool for early-stage lung cancer
2006-06-12

Prognostic value of FDG-PET scan imaging in lymphoma patients undergoing autologous stem cell transplantation

David L. Porter, Edward A. Stadtmauer, Alison Wakoff Loren, Selina Luger
2006-11-14

18F-FDG PET for assessment of therapy response and preoperative re-evaluation after neoadjuvant radio-chemotherapy in stage III non-small cell lung cancer
2006-04-01

Predictive value of 18-fluoro-deoxy-glucose-positron emission tomography (18F-FDG-PET) in the identification of responders to chemoradiation therapy for the treatment of locally advanced esophageal cancer
2006-09-01

Redistribution of nucleoside transporters to the cell membrane provides a novel approach for imaging thymidylate synthase inhibition by positron emission tomography
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Counting heads in the war against cancer: defining the role of annexin A5 imaging in cancer treatment and surveillance

Jagat Narula
2006-07-01

In vivo tumor angiogenesis imaging with site-specific labeled (99m)Tc-HYNIC-VEGF.
2006-07-01

Alphavbeta3-integrin imaging: a new approach to characterise angiogenesis?
2006-10-01

In vitro and in vivo characterization of 64Cu-labeled Abegrin, a humanized monoclonal antibody against integrin alpha v beta 3.

Xiaoyuan Chen
2006-04-01

Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects

Xiaoyuan Chen
2006-11-01

How molecular imaging is speeding up antiangiogenic drug development

Xiaoyuan Chen
2006-06-22

Clinical molecular imaging with positron emission tomography
2006-07-01

Imaging biomarkers as surrogate endpoints for drug development
2006-07-01

Positron emission tomography as an imaging biomarker
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Monitoring tumor glucose utilization by positron emission tomography for the prediction of treatment response to epidermal growth factor receptor kinase inhibitors
2006-04-01

Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia

Daniel J. Hicklin
2006-01-01

Blood flow changes in hepatocellular carcinoma after the administration of thalidomide assessed by reperfusion kinetics during microbubble infusion: preliminary results

Michele Bertolotto
2006-09-22

Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging

Martine Lamfers, Ralph Weissleder, Clemens M F Dirven
2005-01-01

Magnetic resonance and fluorescence based molecular imaging technologies

Ralph Weissleder, David E Sosnovik

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